Cambridge, UK : 23 - 26 June 2019
FULL PROGRAMME AND SPEAKER ABSTRACTS
Scientific Programme Committee
Trey Ideker UC San Diego, USA
"Interpreting the cancer genome through physical and functional models of the cancer cell"
INDUSTRY SPOTLIGHT 1 - ILLUMINA
Nana Akumanyi Illumina, UK
“Immuno-Oncology Research Enabled Through Applied Advanced Genomic Techniques”
Session 1: Convergence and Cancer Genomics- big data, artificial intelligence and integration
Chair: Elaine Mardis
Dana Pe'er MSKCC, USA
"Single cell mapping of plasticity in tumors, metastasis, and development"
James Heath ISB, USA
"New Single Cell Methods for Oncology and Immuno-oncology"
Amalie Kai Bentzen Technical University of Denmark, Denmark
Proffered Paper 1: "Simultaneous identification of antigen-specificity and T cell receptor sequence in single cells"
Opening of the Trade Exhibition
Adi Nagler Weizmann Institute, Israel
Proffered Paper 2: "Identification of microbial-derived HLA-bound peptides in melanoma"
Carlos Caldas CRUK CI, UK
"A systems level view of breast cancer through the lens of artificial intelligence"
3 top-scoring abstracts will be presented in short 'flash talks' of 3 minutes each.
Industry SYMPOSIUM 1 - Thermo Fisher
Tim Looney Thermo Fisher Scientific, USA
"Multi-Dimensional Assays and Potential Biomarkers for Immunotherapy”
POSTER DISCUSSION SESSION 1
Posters 1-67 will be presented. Tea/coffee served at 14:45
Session 2: Clinical Cancer Genomics I
Chair: Daniela Thommen
Charles Swanton The Francis Crick Institute, UK
"Chromosomal instability and genome plasticity in cancer evolution, immune evasion and metastasis"
Stephanie Hilz UCSF, USA
Proffered Paper 3: "The 3D evolution of glioma cell populations"
James Brenton CRUK CI, UK
"Detecting active mutational processes in high grade serous ovarian carcinoma"
"What is the perfect biomarker for response to immune checkpoint blockade therapy?"
INDUSTRY SPOTLIGHT 2 - FLUIDIGM
Anna Piskorz CRUK CI, UK
"Advancing cancer research with flexible and efficient nanoscale automation on the Juno™ System"
Session 3: Clinical Cancer Genomics II
Chair: Yardena Samuels
Shankar Balasubramanian CRUK CI, UK
Richard Gilbertson CRUK CI, UK
“Mapping the origins and treatment of brain tumours”
Yu Fu EMBL-EBI, UK
Proffered Paper 4: "Molecular and clinical associations with histopathological images"
Session 4: Immune Genomics of Cancer I
Chair: James Brenton
Jennifer Wargo The University of Texas MD Anderson Cancer Center, USA
"Understanding the complexities of response to cancer therapy: the organism as a holobiont"
Yardena Samuels Weizmann Institute, Israel
"Towards Deciphering the Neo-Antigenic and Microbial Landscapes in Melanoma"
Oscar Manuel Rueda University of Cambridge, UK
Proffered Paper 5: "Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups"
Abstracts 68-70 will be presented in short ‘flash talks’ of 3 minutes each.
Industry SYMPOSIUM 2 - Nanostring technologies
Jim White Nanostring, UK
GeoMx™ and nCounter®- revolutionary technology to unravel the spatial molecular and cellular interplay of the tumor microenvironment
POSTER DISCUSSION SESSION 2
Posters 68-135 will be presented. Tea/coffee served at 15:00
Session 5: Immune Genomics of Cancer II
Chair: Itay Tirosh
Pia Kvistborg NKI, Netherlands
"The tumor specific T cell response"
Michal Bassani-Sternberg Ludwig Institute for Cancer Research Lausanne, Switzerland
"Proteogenomics and Immunopeptidomics for the development of personalized cancer immunotherapy"
Keren Yizhak Broad Institute of Harvard and MIT, USA
Proffered Paper 6: "RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues"
Daniela Thommen NKI, Netherlands
"Determinants for immunological response to immune checkpoint blockade in human cancer"
Presentation of award certificates
Meet the Experts
Carlos Caldas & Yardena Samuels
An interactive session where our two experts will share from their personal and professional perspectives on the path to scientific leadership.
Session 6: Single-cell analysis of cancers
Chair: Carlos Caldas
John Marioni EMBL-EBI, UK
"Using single-cell RNA-sequencing to provide insight into cell fate"
Itay Tirosh Weizmann Institute, Israel
"Understanding glioma by single cell RNA-seq"
Gabriele Picco Wellcome Trust Sanger Institute, UK
Proffered Paper 7: "The Werner Syndrome RecQ helicase is a synthetic lethal target in MMR-deficient tumors"
Sam Behjati Wellcome Sanger Institute, UK
“The Single Cancer Cell Transcriptome”
EMBO Keynote Lecture
Amos Tanay Weizmann Institute, Israel
"Single cell genomics and epigenomics approaches to understand tumorigenic processes"
Scientific Programme Committee
LUNCH & DEPART
Travel Grant application deadline:
19 April 2019
Abstract submission deadline:
16 May 2019
17 May 2019
A session at Cancer Genomics 2015
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The EACR is grateful for the continued support of its Industry Partners: