POSTER VIEWING

until 09:15

INDUSTRY SPOTLIGHT 1 - ILLUMINA

Nana Akumanyi Illumina, UK

“Immuno-Oncology Research Enabled Through Applied Advanced Genomic Techniques”

Session 1: Convergence and Cancer Genomics- big data, artificial intelligence and integration

Chair: Elaine Mardis

Dana Pe'er MSKCC, USA

"Single cell mapping of plasticity in tumors, metastasis, and development"

James Heath ISB, USA

"New Single Cell Methods for Oncology and Immuno-oncology"

Amalie Kai Bentzen Technical University of Denmark, Denmark

Proffered Paper 1: "Simultaneous identification of antigen-specificity and T cell receptor sequence in single cells"

EXHIBITOR INTRODUCTIONS

COFFEE BREAK

Opening of the Trade Exhibition

Adi Nagler Weizmann Institute, Israel

Proffered Paper 2: "Identification of microbial-derived HLA-bound peptides in melanoma"

Carlos Caldas CRUK CI, UK

"A systems level view of breast cancer through the lens of artificial intelligence"

POSTER SPOTLIGHTS

3 top-scoring abstracts will be presented in short 'flash talks' of 3 minutes each.

Industry SYMPOSIUM 1 - Thermo Fisher

Tim Looney Thermo Fisher Scientific, USA

"Multi-Dimensional Assays and Potential Biomarkers for Immunotherapy”

LUNCH

POSTER DISCUSSION SESSION 1

Posters 1-67 will be presented. Tea/coffee served at 14:45

Session 2: Clinical Cancer Genomics I

Chair: Daniela Thommen

Keynote Lecture

Charles Swanton The Francis Crick Institute, UK

"Chromosomal instability and genome plasticity in cancer evolution, immune evasion and metastasis"

Stephanie Hilz UCSF, USA

Proffered Paper 3: "The 3D evolution of glioma cell populations"

James Brenton CRUK CI, UK

"Detecting active mutational processes in high grade serous ovarian carcinoma"

DISCUSSION FORUM

until 17:30

"What is the perfect biomarker for response to immune checkpoint blockade therapy?"

POSTER VIEWING

until 09:15

INDUSTRY SPOTLIGHT 2 - FLUIDIGM

Anna Piskorz CRUK CI, UK

"Advancing cancer research with flexible and efficient nanoscale automation on the Juno™ System"

Session 3: Clinical Cancer Genomics II

Chair: Yardena Samuels

Shankar Balasubramanian CRUK CI, UK

Richard Gilbertson CRUK CI, UK

“Mapping the origins and treatment of brain tumours”

Yu Fu EMBL-EBI, UK

Proffered Paper 4: "Molecular and clinical associations with histopathological images"

COFFEE BREAK

Session 4: Immune Genomics of Cancer I

Chair: James Brenton

Jennifer Wargo The University of Texas MD Anderson Cancer Center, USA

"Understanding the complexities of response to cancer therapy: the organism as a holobiont"

Yardena Samuels Weizmann Institute, Israel

"Towards Deciphering the Neo-Antigenic and Microbial Landscapes in Melanoma"

Oscar Manuel Rueda University of Cambridge, UK

Proffered Paper 5: "Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups"

POSTER SPOTLIGHTS

Abstracts 68-70 will be presented in short ‘flash talks’ of 3 minutes each.

Industry SYMPOSIUM 2 - Nanostring technologies

Jim White Nanostring, UK

GeoMx™ and nCounter®- revolutionary technology to unravel the spatial molecular and cellular interplay of the tumor microenvironment

LUNCH

POSTER DISCUSSION SESSION 2

Posters 68-135 will be presented. Tea/coffee served at 15:00

Session 5: Immune Genomics of Cancer II

Chair: Itay Tirosh

Pia Kvistborg NKI, Netherlands

"The tumor specific T cell response"

Michal Bassani-Sternberg Ludwig Institute for Cancer Research Lausanne, Switzerland

"Proteogenomics and Immunopeptidomics for the development of personalized cancer immunotherapy"

Keren Yizhak Broad Institute of Harvard and MIT, USA

Proffered Paper 6: "RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues"

Keynote Lecture

Daniela Thommen NKI, Netherlands

"Determinants for immunological response to immune checkpoint blockade in human cancer"

Conference Dinner

Presentation of award certificates

POSTER VIEWING

Meet the Experts

Carlos Caldas & Yardena Samuels

An interactive session where our two experts will share from their personal and professional perspectives on the path to scientific leadership.

Session 6: Single-cell analysis of cancers

Chair: Carlos Caldas

John Marioni EMBL-EBI, UK

"Using single-cell RNA-sequencing to provide insight into cell fate"

Itay Tirosh Weizmann Institute, Israel

"Understanding glioma by single cell RNA-seq"

COFFEE BREAK

Gabriele Picco Wellcome Trust Sanger Institute, UK

Proffered Paper 7: "The Werner Syndrome RecQ helicase is a synthetic lethal target in MMR-deficient tumors"

Sam Behjati Wellcome Sanger Institute, UK

“The Single Cancer Cell Transcriptome”

EMBO Keynote Lecture

Amos Tanay Weizmann Institute, Israel

"Single cell genomics and epigenomics approaches to understand tumorigenic processes"

Closing Summary

Scientific Programme Committee

LUNCH & DEPART