Cancer Genomics 2019

Cambridge, UK : 23 - 26 June 2019

Scientific Programme

Sunday 23rd June 2019

15:00

Registration

Tea/coffee available

17:00

Conference welcome

Scientific Programme Committee

17:15

Keynote Lecture

Trey Ideker UC San Diego, USA

"Interpreting the cancer genome through physical and functional models of the cancer cell"

18:00

NETWORKING RECEPTION

19:00

Welcome dinner

Monday 24th June 2019

08:30

POSTER VIEWING

until 09:15

09:00

INDUSTRY SPOTLIGHT 1 - ILLUMINA

Nana Akumanyi Illumina, UK

“Immuno-Oncology Research Enabled Through Applied Advanced Genomic Techniques”

09:15

Session 1: Convergence and Cancer Genomics- big data, artificial intelligence and integration

Chair: Elaine Mardis

09:15

Dana Pe'er MSKCC, USA

"Single cell mapping of plasticity in tumors, metastasis, and development"

09:45

James Heath ISB, USA

"New Single Cell Methods for Oncology and Immuno-oncology"

10:15

Amalie Kai Bentzen Technical University of Denmark, Denmark

Proffered Paper 1: "Simultaneous identification of antigen-specificity and T cell receptor sequence in single cells"

10:30

EXHIBITOR INTRODUCTIONS

10:45

COFFEE BREAK

Opening of the Trade Exhibition

11:15

Adi Nagler Weizmann Institute, Israel

Proffered Paper 2: "Identification of microbial-derived HLA-bound peptides in melanoma"

11:30

Carlos Caldas CRUK CI, UK

"A systems level view of breast cancer through the lens of artificial intelligence"

12:00

POSTER SPOTLIGHTS

3 top-scoring abstracts will be presented in short 'flash talks' of 3 minutes each.

12:15

Industry SYMPOSIUM 1 - Thermo Fisher

Tim Looney Thermo Fisher Scientific, USA

"Multi-Dimensional Assays and Potential Biomarkers for Immunotherapy”

12:45

LUNCH

13:45

POSTER DISCUSSION SESSION 1

Posters 1-67 will be presented. Tea/coffee served at 14:45

15:15

Session 2: Clinical Cancer Genomics I

Chair: Daniela Thommen

15:15

Keynote Lecture

Charles Swanton The Francis Crick Institute, UK

"Chromosomal instability and genome plasticity in cancer evolution, immune evasion and metastasis"

16:00

Stephanie Hilz UCSF, USA

Proffered Paper 3: "The 3D evolution of glioma cell populations"

16:15

James Brenton CRUK CI, UK

"Detecting active mutational processes in high grade serous ovarian carcinoma"

16:45

DISCUSSION FORUM

until 17:30

"What is the perfect biomarker for response to immune checkpoint blockade therapy?"

Tuesday 25th June 2019

08:30

POSTER VIEWING

until 09:15

09:00

INDUSTRY SPOTLIGHT 2 - FLUIDIGM

Anna Piskorz CRUK CI, UK

"Advancing cancer research with flexible and efficient nanoscale automation on the Juno™ System"

09:15

Session 3: Clinical Cancer Genomics II

Chair: Yardena Samuels

09:15

Shankar Balasubramanian CRUK CI, UK

09:45

Richard Gilbertson CRUK CI, UK

“Mapping the origins and treatment of brain tumours”

10:15

Yu Fu EMBL-EBI, UK

Proffered Paper 4: "Molecular and clinical associations with histopathological images"

10:30

COFFEE BREAK

11:00

Session 4: Immune Genomics of Cancer I

Chair: James Brenton

11:00

Jennifer Wargo The University of Texas MD Anderson Cancer Center, USA

"Understanding the complexities of response to cancer therapy: the organism as a holobiont"

11:30

Yardena Samuels Weizmann Institute, Israel

"Towards Deciphering the Neo-Antigenic and Microbial Landscapes in Melanoma"

12:00

Oscar Manuel Rueda University of Cambridge, UK

Proffered Paper 5: "Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups"

12:15

POSTER SPOTLIGHTS

Abstracts 68-70 will be presented in short ‘flash talks’ of 3 minutes each.

12:30

Industry SYMPOSIUM 2 - Nanostring technologies

Jim White Nanostring, UK

GeoMx™ and nCounter®- revolutionary technology to unravel the spatial molecular and cellular interplay of the tumor microenvironment

13:00

LUNCH

14:00

POSTER DISCUSSION SESSION 2

Posters 68-135 will be presented. Tea/coffee served at 15:00

15:30

Session 5: Immune Genomics of Cancer II

Chair: Itay Tirosh

15:30

Pia Kvistborg NKI, Netherlands

"The tumor specific T cell response"

16:00

Michal Bassani-Sternberg Ludwig Institute for Cancer Research Lausanne, Switzerland

"Proteogenomics and Immunopeptidomics for the development of personalized cancer immunotherapy"

16:30

Keren Yizhak Broad Institute of Harvard and MIT, USA

Proffered Paper 6: "RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues"

16:45

Keynote Lecture

Daniela Thommen NKI, Netherlands

"Determinants for immunological response to immune checkpoint blockade in human cancer"

19:30

Conference Dinner

Presentation of award certificates

Wednesday 26th June 2019

08:30

POSTER VIEWING

09:00

Meet the Experts

Carlos Caldas & Yardena Samuels

An interactive session where our two experts will share from their personal and professional perspectives on the path to scientific leadership.

09:40

Session 6: Single-cell analysis of cancers

Chair: Carlos Caldas

09:40

John Marioni EMBL-EBI, UK

"Using single-cell RNA-sequencing to provide insight into cell fate"

10:10

Itay Tirosh Weizmann Institute, Israel

"Understanding glioma by single cell RNA-seq"

10:40

COFFEE BREAK

11:10

Gabriele Picco Wellcome Trust Sanger Institute, UK

Proffered Paper 7: "The Werner Syndrome RecQ helicase is a synthetic lethal target in MMR-deficient tumors"

11:25

Sam Behjati Wellcome Sanger Institute, UK

“The Single Cancer Cell Transcriptome”

11:55

EMBO Keynote Lecture

Amos Tanay Weizmann Institute, Israel

"Single cell genomics and epigenomics approaches to understand tumorigenic processes"

12:40

Closing Summary

Scientific Programme Committee

12:50

LUNCH & DEPART

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