Welcome to the European Association for Cancer Research
Connecting cancer researchers together
A Matter of Life or Death: Mechanisms, Models and Therapeutic Opportunities
Bergamo, Italy : 12 - 14 February 2020
Scientific Programme
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FULL PROGRAMME AND ABSTRACTS
Click here to download the Full Programme and Abstract Book for the conference
Q&A: 14:10 - 14:25
REGISTRATION
until 13:30
WELCOME LUNCH & TRADE EXHIBITION
CONFERENCE WELCOME
Scientific Programme Committee
SESSION 1: Cancer metabolism, autophagy and tumor microenvironment
Chair: Verena Jendrossek
The EMBO Keynote Lecture
Sharon Tooze The Francis Crick Institute, UK
"Molecular mechanisms of autophagosome formation"
Katja Simon Kennedy Institute of Rheumatology, UK
“Autophagy in cell fate decisions in the immune & hematopoietic system"
Q&A: 14:45 - 14:55
Monica Vara-Perez VIB – KULeuven, Belgium
Proffered Paper 1: "BNIP3 sustains HIF1α to promote melanoma growth and dissemination"
Q&A: 15:05 - 15:10
EXHIBITOR INTRODUCTIONS
60-second intro by each company
COFFEE BREAK & TRADE EXHIBITION
Patrizia Agostinis VIB – KULeuven, Belgium
"Autophagy in tumor angiogenesis"
Q&A: 16:10 - 16:20
Almut Schulze DKFZ, Germany
“Understanding the complex role of lipid metabolism in cancer”
Q&A: 16:40 - 16:50
Sarah-Maria Fendt VIB-KU Leuven, Belgium
“The role of metabolism in metastasis formation”
Q&A: 17:10 - 17:20
POSTER SPOTLIGHTS
3 top-scoring abstracts (posters 1-3) presented in 3 minute 'flash talks'
NETWORKING RECEPTION
An opportunity to make new connections over a drink and some light food
POSTER DISCUSSION SESSION 1
until 19:30
Posters 1-30 will be presented
POSTER VIEWING & TRADE EXHIBITION
until 09:00
Coffee / tea available
INDUSTRY SPOTLIGHT - VectorBuilder
Matthew Wheeler
"VectorBuilder - Advances in vector construction and virus packaging"
SESSION 2: Cell death mechanisms
Chair: Peter de Keizer
Keynote Lecture
René Bernards NKI, Netherlands
“Exploiting senescence for the treatment of cancer”
Q&A: 09:30 - 09:45
Nataly Kravchenko-Balasha The Hebrew University of Jerusalem, Israel
Proffered Paper 2: "Deciphering the intra-tumor and inter-patient signaling heterogeneity in cancer for the rational design of patient specific drug cocktails"
Q&A: 09:55 - 10:00
David Wallach Weizmann Institute of Science, Israel
“Novel insights into the functional roles of the signaling pathway for necroptotic death"
Q&A: 10:20 - 10:30
COFFEE BREAK & TRADE EXHIBITION
Marion MacFarlane MRC Toxicology Unit, UK
"Uncovering the Therapeutic Potential of BH3-mimetics in Patient-relevant Pre-clinical Models of Mesothelioma''
Q&A: 11:25 - 11:35
Samuel Sidi Icahn School of Medicine at Mount Sinai, USA
Proffered Paper 3: "FANCI Functions as a Repair/Apoptosis Switch in Response to DNA Crosslinks"
Q&A: 11:45 - 11:50
Dagmar Kulms TU Dresden, Germany
“Caspase-8 promotes progression of p53-proficient tumors"
Q&A: 12:10 - 12:20
POSTER SPOTLIGHTS
3 top-scoring abstracts (posters 31-33) presented in 3 minute 'flash talks'
LUNCH & TRADE EXHIBITION
POSTER DISCUSSION SESSION 2
Posters 31-59 will be presented
SESSION 3: Senescence, cancer and therapeutic targeting
Chair: Patrizia Agostinis
Manuel Serrano ICREA Professor, IRB Barcelona, Spain
“Cellular senescence as a driver of multiple human diseases"
Q&A: 14:50 - 15:00
Marco Demaria ERIBA/UMCG, The Netherlands
"Modulating senescence-associated phenotypes to prevent side effects of cancer therapy"
Q&A: 15:20 - 15:30
Olivier E. Pardo Imperial College, UK
Proffered Paper 4: "Targeting the S6 kinase, RSK4, prevents chemoresistance and metastasis in lung cancer"
Q&A: 15:40 - 15:45
COFFEE BREAK & TRADE EXHIBITION
Laura Conti MBC, University of Torino, Italy
Proffered Paper 5: "The immunotargeting of the xCT cystine/glutamate antiporter targets cancer stem cells and potentiates the efficacy of Her2-targeted immunotherapies in breast cancer"
Q&A: 16:25 - 16:30
Peter de Keizer UMC Utrecht, The Netherlands
"Targeting Heterogeneity in Senescence against Aging and Cancer"
Q&A: 16:50 - 17:00
Daniel Murphy CRUK Beatson Institute, UK
"Partners in crime: MYC, RAS and cell-extrinsic mechanisms of oncogenic cooperation"
Q&A: 17:20 - 17:30
DISCUSSION FORUM
until 18:30
Chaired by Patrizia Agostinis, the panel of invited speakers will tackle this important question.
“Novel frontiers in regulated cell death and senescence: what is the desirable type of cell inactivation in cancer therapy?”
Conference Dinner
Optional ticketed dinner at Taverna Valtellinese
POSTER VIEWING & TRADE EXHIBITION
until 09:00
Coffee / tea available
INDUSTRY SPOTLIGHT - Tecan
Stefan Haberstock
"Optimization of drug titration in cell based assays"
MEET THE EXPERTS TALK
Silvia Formenti & Verena Jendrossek
An interactive session with a focus on women in science where our two experts will share from their personal and professional perspectives on the path to scientific leadership.
SESSION 4: Harnessing cell death and cancer vulnerabilities for cancer therapy
Chair: Marion MacFarlane
Clemens Schmitt MDC Berlin, Germany
"Post-senescence: a matter of life and death"
Q&A: 10:05 - 10:15
Verena Jendrossek Universität Duisburg-Essen, Germany
"Novel opportunities for a biologic optimization of radiotherapy"
Q&A: 10:35 - 10:45
COFFEE BREAK & TRADE EXHIBITION
Serk In Park Korea University College of Medicine, South Korea
Proffered Paper 6: "Mobilization of Monocytic Myeloid-Derived Suppressor Cells (MDSC) Is Regulated by Osteoblast Activation by PTH1R"
Q&A: 11:25 - 11:30
Brent Stockwell Columbia University, USA
“Ferroptosis: mechanisms and therapeutic potential"
Q&A: 11:50 - 12:00
Closing Keynote
Silvia C. Formenti Weill Cornell Medicine, USA
“Radiotherapy to convert the tumor into an in situ vaccine"
Q&A: 12:30 - 12:45
Conference Summary
Scientific Programme Committee
LUNCH & DEPART
Key dates
Travel Grant application deadline:
02 December 2019
Abstract submission deadline:
02 December 2019
Registration deadline:
13 January 2020
