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Berlin, Germany : 1 - 3 November 2022
To download and print the programme, use the links below.
Listed times are in Central European Time (CET)
REGISTRATION & WELCOME LUNCH
CONFERENCE WELCOME
Session 1: Targeting organelles for therapy
Chair: Hugues de Thé
OPENING KEYNOTE LECTURE
Anthony Letai Harvard University, USA
"The mitochondrial basis for clinical efficacy of conventional chemotherapy"
Q&A: 13:40-13:55
Maria Rescigno Humanitas University, Italy
"Microbiota in cancer progression and metastasis"
Q&A: 14:15 - 14:25
Martin Higgs University of Birmingham, UK
Proffered Paper 1: "A novel epigenetic mechanism for PARPi resistance in BRCA1-deficient tumour cells"
Q&A: 14:35 - 14:40
EXHIBITOR INTRODUCTIONS
60-second intro pitches by each company
COFFEE BREAK & TRADE
Jean-Emmanuel Sarry (Virtual Presentation) CRCT, France
"Mitochondrial adaptation as a Darwinian mechanism of resistance to drugs in leukemia"
Q&A: 15:40 - 15:50
Poster Spotlights
3 top abstracts presented as 3 minute flash talks
Meet the Expert talk
Jos Jonkers & Maria Rescigno
Prof Jonkers and Prof. Dr. Rescigno will host an informal session where they will both share their own personal and professional experiences of their paths to scientific leadership.
Q&A: 16:30 - 16:45
Welcome Reception
Drinks reception with buffet served from 17:00
POSTER DISCUSSION SESSION 1
Listed times are in Central European Time (CET)
Poster Viewing
Posters may be freely viewed
Session 2: Breast cancer: Old targets, new approaches
Chair: Sandra Demaria
Jason Carroll University of Cambridge, UK
"The role of transcription factors in primary ER+ breast cancer and in metastasis"
Q&A: 09:20 - 09:30
Mathias Dahlmann Max-Delbrück-Center for Molecular Medicine, Germany
Proffered Paper 2: "PDX models as suitable tools to identify response patterns and novel treatment options in highly heterogeneous tumors"
Q&A: 09:40 - 09:45
Cathrin Brisken EPFL, Switzerland
"Taming hormone-sensitive breast cancer"
Q&A: 10:05 - 10:15
Jos Jonkers NKI, Netherlands
"Understanding and overcoming resistance to PARP inhibitors in cancer therapy"
Q&A: 10:35 - 10:45
COFFEE BREAK & TRADE
The EMBO Keynote Lecture
Fatima Mechta-Grigoriou Institut Curie, France
"Role of fibroblast heterogeneity in immunosuppression and resistance to immunotherapy"
Q&A: 11:35-11:45
Stefan Florian Charité University Hospital, Germany
Proffered Paper 3: "Microtubule binding drugs as a phenotype specific targeted cancer therapy"
Q&A: 11:55 - 12:00
Lisa Derosa Institute Gustave Roussy, France
"Targeting Gut and Tumour Microbiota to Increase Cancer Immunotherapy Efficacy"
Q&A: 12:20 - 12:30
POSTER SPOTLIGHTS
3 top abstracts presented as 3 minute flash talks
Lunch
POSTER DISCUSSION SESSION 2
Session 3: New Lives for Chemo
Chair: Sophie Postel-Vinay
Michael Hemann MIT, USA
"What chemotherapy can tell us about tumor cell dependencies"
Q&A: 15:30 - 15:40
INDUSTRY SPOTLIGHT - Standard BioTools
Melissa Klug
"Ready-to-use 45+ flow cytometry marker panels to measure activation, cytokine production and cytotoxicity from <300ul of whole blood"
COFFEE BREAK & TRADE
Maria Secrier UCL Genetics Institute, UK
Proffered Paper 4: "A novel quiescence signature captures rapid drug tolerance development in cancer persister cells"
Q&A: 16:50 - 16:55
Vinu Jose (Virtual Presentation) Institut Jules Bordet - Universite Libre du Bruxelles, Belgium
Proffered Paper 5: "Microtubule targetting agents affect the clinical benefit of immune response in early breast cancer"
Q&A: 17:05 - 17:10
Hugues de Thé Institut Jean Bernard, France
"From nuclear architecture to leukemia cure: emerging roles of PML"
Q&A: 17:30 - 17:40
Conference Dinner
30-minute drinks reception before the dinner at 19:00. Optional ticketed event.
Listed times are in Central European Time (CET)
Poster viewing
Session 4: Exploiting cytoplasmic DNA sensing for therapy
Chair: Sophie Postel-Vinay
Kalle Sipila King's College London, UK
Proffered Paper 6: "Mutational heterogeneity and drug response in oral squamous cell carcinoma"
Q&A: 09:55 - 10:00
Sophie Postel-Vinay Gustave Roussy, France
"Harnessing genetic vulnerabilities in immuno-oncology: novel therapeutic opportunities"
Q&A: 10:20 - 10:30
COFFEE BREAK & TRADE
Priyanka Bhosale Kings College London, UK
Proffered Paper 7: "Apoptosis of tumour infiltrating lymphocytes is a mechanism of tumour resistance in OSCC"
Q&A: 11:10 - 11:15
Olivia Ciampa Garvan Institute of Medical Research, Australia
Proffered Paper 8: "Senescence Reprogramming in ER+ Breast Cancer"
Q&A: 11:25 - 11:30
Closing Keynote Lecture
Sandra Demaria Weill Cornell Medicine, USA
"Cancer cell-intrinsic and extrinsic innate immune activation induced by radiation"
Q&A: 12:00 - 12:15
SUMMARY & CLOSE
Depart
Travel Grant application deadline:
11 September 2022
Abstract submission deadline:
13 September 2022
Registration deadline:
30 September 2022
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