On the Day Guide

Welcome to EACR-Boehringer Ingelheim 'Drugging and Regulating the MAP Kinase Pathway' 2023! This page brings together all the information you’ll need while attending this EACR Virtual Conference. 

Quick Links

• Scientific Programme
• Virtual Poster Discussion Sessions
  • Session 1 Posters
  • Session 2 Posters​
• Digital Abstracts and Posters (Login required for access)
• Participant List (You will receive the password at the start of the conference)
• Code of Conduct

Zoom

We run our EACR Virtual Conferences across two Zoom formats – Webinars (for the conference talks) and Meetings (for our poster discussion sessions). As an attendee during the webinar, you won’t be able to switch on your camera and will need to have your microphone enabled to ask questions. During the Poster Discussion Sessions, you will be in control of your own camera and microphone. You will need to have both switched on to get the most out of these sessions. 

Accessing the Webinar

Approximately 24 hours before the start of each day of the conference, you should receive an email from Zoom with your link to access the conference webinar. As this is an automated email, it might be sorted into your junk folder. If you have not received your email by the morning of the conference, then please email Christopher.Iliffe@eacr.org. This webinar link is specific to you and should not be shared with anyone else.

If you click on this link before the conference is due to start, you will see a holding screen. Once EACR has started the webinar, the system will automatically move you into the conference space. If you need to leave the conference, you can rejoin later using the same link.

Asking Questions

There are two ways that you can ask questions to our speakers during the conference talks.

If you want to ask your question live, then please use the ‘Raise Hand’ button. This might be located at the top or bottom of your screen. The Chair will invite you to ask your question, and the EACR will enable your microphone.

If you do not want to ask your question live, then use the Q&A box. This might be found at the bottom of your screen. You will have the option to ask your question anonymously if that is your preference. The Chair will then read questions from the Q&A box on your behalf.

Virtual Poster Discussion Sessions

Tuesday 21 February, 17:45-18:45 CET
Wednesday 22 February, 13:00-14:00 CET

The Poster Discussion Sessions are scheduled to take place at the end of Day 1 and the beginning of Day 2 of the conference. They will each be held as a seperate Zoom meeting. You will receive the links to join these meetings in the email sent to you a week before the conference. During the Virtual Poster Discussion Sessions, each poster presenter will have their very own 'Breakout Room' where they will be displaying their poster. All attendees will have full control over their camera and microphone, be able to communicate using the chat, and navigate across the breakout rooms to view each poster and talk to the poster presenter.

When you first enter the meeting, you will go straight to the “Lobby”. EACR staff will be there throughout the session should you have any questions. Details of each of the posters on display in the session and their relevant breakout rooms will also be shown on the screen in this main area. You can also access the list of posters via our Online Abstract Book and through our ‘On the Day’ guide (you can find the lists further down this page!).

Conference participants are invited to join any of the rooms to browse the posters, discuss the work on show and make new connections. To navigate to a specific breakout room, click on the ‘Breakout Room’ button and then on the specific room you would like to join. Zoom will then move you to that breakout room. Keep in mind that each poster discussion session only lasts 1 hour, so make sure you leave yourself plenty of time to browse!

If you are a Poster Presenter, you will have your own designated breakout room which corresponds to your poster number. This space is entirely yours and can be used to present your research however you think is best! We recommend sharing your poster as a PowerPoint slide or presentation. 

Feedback from our previous Virtual Poster Discussion Sessions:

"The poster sessions were extremely well-organised and interactive. This type of session provides a very inspiring platform to interact with other people working in the field more openly and facilitates great scientific exchange."

"I felt fully involved in the conference most especially during the breakout session where I was able to present my work and also get to discuss it with other great minds."

"The virtual social and networking experiences provided me with valuable connections and insights that I wouldn’t have been able to gain otherwise."

Poster Discussion Session 1: Tuesday 21 February 2023

17:45 – 18:45 CET

Posters on display:

Poster 01 – Coralie Dessauges “Optogenetic actuator - ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics”

Poster 02 - Irati Macaya Erro “Signature-driven repurposing of Midostaurin (PKC412) for combination with MEK1/2 and KRASG12C inhibitors in lung cancer”

Poster 03 – Naiara Perurena Aizcorbe “USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities”

Poster 04 – Lynda Addou-Klouche “Targeting PI3K/AKT/mTOR signaling pathway in HER2+ and Triple- Negative breast cancer subtypes”

Poster 05 – Joaquin Teixidó Calvo “Dissecting drug tolerance and resistance mechanisms in melanoma cells targeted with MAPK-pathway inhibitors”

Poster 06 – Annie Wai Yeeng Chai “Targeting PTPN11 in oral squamous cell carcinoma”

Poster 07 – Helena Codina Martínez “Combinatory MAPK and mTOR pathway inhibition in a preclinical model of intestinal-type sinonasal adenocarcinoma”

Poster 08 – Rodrigo Entrialgo “The lipid transporter PITPNC1 links KRAS oncogene to MYC and MTOR in lung and pancreatic cancer”

Poster 09 – Romi Gupta “Co-targeting of specific Epigenetic Regulators in combination with CDC7 potently inhibit Melanoma growth”

Poster 10 – Ana Herrero “Characterization of ncRNA-dependent MEK activity in melanoma”

Poster 11 – Fanny Lardinois “Role of methylglyoxal stress in acquired resistance to targeted therapy in colorectal cancer”

Poster 12 – Timofey Lebedev “Identification of drug ERK-dependent toxicity, synergies with ERK inhibitors and resistance mechanisms using pan-cancer cell panel with ERK activity reporter”

Poster 13 – Daria Lehrmann “Systemic MAPK pathway inhibition in an orthotopic murine xenograft model of conjunctival melanoma”

Poster 14 – Elena Martin-Orozco “Differential p38 MAPK signalling and cytokine profile on sensitive versus resistant human leukemic cells”

This session will end at 18:45 CET so please make sure you give yourself enough time to browse each of the posters on display!

Poster Discussion Session 2: Wednesday 22 February 2023

13:00 – 14:00 CET

Before the main programme of scientific talks on Day 2 we will hold our second 60-minute ‘Virtual Poster Discussion Session’, showcasing even more posters submitted for the conference. Please make sure you have received the link to this meeting and that you have joined the session by 13:00 CET.

Posters on display: 

Poster 15 – Kohei Maruyama “Investigation of the novel intrinsic resistance mechanisms to KRAS inhibitor in colorectal cancer”

Poster 16 – Laura Millett “Characterising mutant KRASG12C in genetically engineered mouse models of colorectal cancer”

Poster 17 – Katarina Nikolic “Computer-aided drug design of MAPK1 inhibitors by combined 3D-QSAR analysis and molecular docking”

Poster 18 – Ofra Zoor Novoplansky “Activation of the EGFR/PI3K/AKT pathway limits the efficacy of trametinib treatment in head and neck cancer”

Poster 19 – Senem Noyan “miR-770-5p sensitizes trastuzumab resistant cells via HER2/EGFR/IGF1R bidirectional crosstalk”

Poster 20 – Caroline Nunes-Xavier “Molecular and clinical impact of MAP kinase pathway regulators in pediatric neuroblastoma”

Poster 21 – Andrea Olarte “SOS-RAS GEFs inhibition as a potential therapeutic target in cancer and metabolism”

Poster 22 – Jose Luis Orgaz Bueno “Targeting the cytoskeleton to overcome therapy resistance in melanoma”

Poster 23 – Giulia Pelos “Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment”

Poster 24 – Nikolina Piteša “Characterization of GANT61 Resistant Cell Lines reveals new insights of Hedgehog-GLI and RAS/RAF/MAPK interplay in melanoma”

Poster 25 – Pablo Rodríguez-Ramos “SOS RAS-GEFs play relevant roles in respiratory metabolism in immortalized MEFs”

Poster 26 – Roberto Arriga “Preclinical activities of humanized anti-HER3 antibodies in sarcoma cell lines”

Poster 27 – Klaudia Schossleitner “Endothelial cells show distinct phosphorylation patterns in response to BRAF inhibition”

Poster 28 – Vadim Sumbayev “The impact of the immune checkpoint protein VISTA on MAP kinase and other signalling pathways resulting in downregulation of T cell functions”

Poster 29 – Olivia Villeronce “BRAF V600E mutation promotes colorectal cancer stem cell phenotype”

This session will end at 14:00 CET so please make sure you give yourself enough time to browse each of the posters on display!

There will then be a 10-minute break before we move over to Zoom Webinar for our second day of scientific talks.