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Virtual Event, Worldwide : 21 - 22 February 2023
To download and print the programme, use the links below.
Listed times are in Central European Time (CET)
WELCOME TO DAY ONE
Rene Bernards & Marisol Soengas
Session 1: Signalling
Chairs: Marco Hofmann & Anna Obenauf
Marco Hofmann Boehringer Ingelheim, Austria
"SOS1i combinations enhance the anti-tumor response and overcome resistance"
Q&A 13:25-13:40
Chiara Ambrogio University of Torino, Italy
“Signaling plasticity in pre-clinical models of adaptive and acquired resistance to KRAS-G12C inhibitors”
Q&A 14:00-14:15
Sara Mainardi Netherlands Cancer Institute, Netherlands
Proffered Paper 1: "From bench to bedside and back to bench: identification of potential resistance markers for the SHERPA (SHP2 and ERK inhibition in pancreatic cancer) trial."
Q&A 14:25-14:30
PROGRAMME BREAK
Frank McCormick UC San Francisco, USA
"Targeting KRAS and its immediate effectors"
Q&A 15:05-15:20
Kevan Shokat UC San Francisco, USA
“Drugging undruggable targets in cancer”
Q&A 15:40-15:55
PROGRAMME BREAK
Session 2: Immune Regulation
Chairs: Marisol Soengas & Ralph Neumueller
Caroline Robert Gustave Roussy, France
"Melanoma Persitent cells : Can we track the invisible?"
Q&A 16:30-16:45
Roger Lo UCLA, USA
'Stabilizing the Genome to Prevent Acquired MAPK Inhibitor Resistance'
Q&A 17:05-17:20
Poster Spotlights
3 top abstracts presented as 3-minute flash talks
End of Day 1 Webinar
Once the Webinar has ended we will take a 15-minute break before we begin our Virtual Poster Discussion Session 1
Virtual Poster Discussion Session 1
An informal and interactive 'virtual' opportunity for participants to browse the posters and make new connections. This 60-minute session will be delivered through the Zoom Meeting platform.
END OF DAY ONE
Listed times are in Central European Time (CET)
Virtual Poster Discussion Session 2
An informal and interactive 'virtual' opportunity for participants to browse the posters and make new connections. This 60-minute session will be delivered through the Zoom Meeting platform.
10-minute transition break (Meeting to Webinar)
WELCOME TO DAY TWO
Session 3: Resistance
Chairs: Marco Hofmann & Ralph Neumuller
Antreas Hindoyan Amgen Inc
“Putative mechanisms of acquired resistance to sotorasib in KRAS p.G12C-mutated NSCLC and CRC: plasma biomarker analysis of CodeBreaK 100”
Q&A 14:35-14:50
Paolo Armando Gagliardi Institute of Cell Biology, Switzerland
Proffered Paper 2: "Targeting apoptosis-induced collective MAPK activity waves to improve breast cancer therapy"
Q&A 15:00-15:05
Fernando Calvo Baltanas University of Seville, Spain
Proffered Paper 3: "Validation of SOS1/2 RASGEFs as therapeutic targets in KRASG12D-driven lung adenocarcinoma"
Q&A 15:15-15:20
PROGRAMME BREAK
Anna Obenauf Research Institute of Molecular Pathology, Austria
"Towards rational combination therapies: Understanding tumor evolution during therapy response and resistance"
Q&A 15:55-16:10
Rene Bernards The Netherlands Cancer Institute, Netherlands
"Paradoxical activation of oncogenic signaling as a cancer treatment strategy"
Q&A 16:30-16:45
Julian Downward Francis Crick Institute, UK
"KRAS oncogene signalling and the tumour immune microenvironment in lung cancer"
Q&A 17:05-17:20
SUMMARY AND END OF DAY TWO
Rene Bernards & Anna Obenauf
Abstract submission deadline:
09 January 2023
Registration deadline:
02 February 2023
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