Virtual Event, Worldwide : 13 - 14 February 2024
To download and print the programme, use the links below.
Listed times are in Central European Time (CET)
WELCOME TO DAY ONE
Chair: Jukka Westermarck
Stephin Vervoort Walter and Eliza Hall Institute of Medical Research, Australia
"The Rise of the Anti-Terminators: How CDK12/13 combat transcriptional terminators to keep RNA Polymerase II on course"
Q&A 13:25 - 13:35
Mutsuhiro Takekawa University of Tokyo, Japan
"Transcriptional regulation of immediate-early genes by a novel ERK substrate protein and its failure in cancer"
Q&A 13:55 - 14:05
Tim Lebedev Engelhardt Institute of Molecular Biology, Russia
Proffered Paper 1: "Pan-cancer profiling of ERK1/2 activity with single cell imaging predicts anticancer drug synergy with ERK inhibitors."
Q&A 14:15 - 14:20
Refreshment break
Chair: Chiara Ambrogio
Jukka Westermarck Turku Bioscience Centre, University of Turku, FInland
"DUSP6 inhibition overcomes Neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer"
Q&A 15:00 - 15:10
Mariangela Russo University of Turin, Italy
"Leveraging DNA Damage Response to prevent secondary resistance to MAPK pathway inhibition"
Q&A 15:30 - 15:40
Dan Lu Harvard Medical School, USA
Proffered Paper 2: "Integration of p53 dynamics and modifications regulate temporal therapeutic response"
Q&A 15:50 - 15:55
Refreshment break
Gad Getz Broad Institute, USA
"Finding mechanisms of resistance in cancer"
Q&A 16:35 - 16:45
POSTER SPOTLIGHTS
DAY 1 SUMMARY
Transition break
VIRTUAL POSTER DISCUSSION SESSION ONE
Listed times are in Central European Time (CET)
VIRTUAL POSTER DISCUSSION SESSION TWO
Transition break
WELCOME TO DAY TWO
Chair: Yaara Oren
Bernhard Küster Technical University of Munchen, Germany
"Decrypting drug actions and protein modifications by dose- and time-resolved proteomics"
Q&A 14:25 - 14:35
Jean-Emmanuel Sarry Toulouse Cancer Research Center, France
"Mitochondrial signaling circuits in response to therapy of acute myeloid leukemia."
Q&A 14:55 - 15:05
Alessandra Allotta Royal College of Surgeons in Ireland, Ireland
Proffered Paper 3: "Insights into the biological effect of targeting CDK12 in advanced ER+ breast cancer"
Q&A 15:15 - 15:20
Refreshment break
Chair: Jukka Westermarck
Nikhil Gupta Turku Bioscience Centre. Finland
Proffered Paper 4: "Species-specific differences in Malignant Transformation: Role of PP2A and its implications for cancer therapy"
Q&A 15:50 - 15:55
Yaara Oren Tel Aviv University, Israel
"Identifying the mechanisms underlying persistence potential and drug-induced cellular memory"
Q&A 16:15 - 16:25
Sydney Shaffer University of Pennsylvania, USA
"Tracking the origins of metaplasia and cancer"
Q&A 16:45 - 16:55
Refreshment break
Michelle Arkin University of California San Francisco, USA
"Modulating Cancer Networks with Molecular Glues"
Q&A 17:35 - 17:45
CONFERENCE SUMMARY
Our Scientific Programme Committee members, Jukka Westermarck, Chiara Ambrogio and Yaara Oren will join together to deliver their thoughts and a summary of the meeting.
Abstract submission deadline:
05 January 2024
Registration and Payment deadline:
01 February 2024
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