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Welcome to the European Association for Cancer Research
Europe’s membership association for cancer researchers

Seed and Soil: Mechanisms of Metastasis

Berlin, Germany : 7 - 9 October 2019

Scientific Programme

To download and print the programme, use the links below.

13:00

Registration

Tea/coffee available

14:30

Conference Welcome

Scientific Programme Committee

Session 1 - Metastasis Initiation

Chair: Janine Terra Erler

14:40

The EMBO Keynote Lecture

Cedric Blanpain ULB, Belgium

"Tumor transition states and metastasis"

15:25

Jonathan Sleeman University of Heidelberg, Germany

"Matrix-Assisted Autocrine Signaling"

15:55

Luigi Ombrato The Francis Crick Institute, UK

Proffered Paper 1: "A novel in vivo labelling system reveals tissue parenchyma stem cell features in the metastatic niche"

16:10

EXHIBITOR INTRODUCTIONS

60-second intro pitches by each company

16:20

COFFEE BREAK

Trade exhibition opens at 16:20

16:50

Rosandra Kaplan NCI/NIH, USA

"Stromal and Immune Cell Plasticity in the Pre Metastatic Niche and Metastatic Progression"

17:20

Christoph Klein University of Regensburg, Germany

"Mechanisms of early metastatic spread and colony formation: insights from the analysis of disseminated cancer cells"

17:50

Sarah Weischer Radboudumc, Netherlands

Proffered Paper 2: "An intravascular tumor niche identified by deep-tumor multiphoton endomicroscopy"

18:05

Jim Norman Beatson Institute, UK

"A role for integrin trafficking in metastatic niche priming"

18:35

POSTER SPOTLIGHTS

Three top-scoring abstracts presented in 3 minute 'flash talks'

18:45

WELCOME RECEPTION

with drinks and a hot buffet dinner

19:15

POSTER DISCUSSION SESSION 1

08:30

POSTER VIEWING

Tea/coffee available

Session 2 - Metastasis Maintenance & Formation

Chair: Andreas Trumpp

09:00

Sarah-Maria Fendt VIB-KU Leuven, Belgium

"The role of metabolism is metastasis formation"

09:30

Eduard Batlle IRB Barcelona, Spain

"Immune evasion and metastasis in colorectal cancer"

10:00

Keynote Lecture

Caroline Dive CRUK Manchester Institute, UK

"New approaches to studying lung cancer metastasis using circulating tumour cells"

10:45

COFFEE BREAK

11:20

Anna Lorentzen Aarhus University, Denmark

Proffered Paper 3: "Single-cell polarity as a pro-metastatic feature of circulating tumour cells"

11:35

Julio Aguirre-Ghiso The Icahn School of Medicine at Mount Sinai, USA

"Dormant DCCs and adult stem cell niches: a homeostatic seed and soil partnership"

12:05

Gabriele Bergers VIB-KU Leuven Center for Cancer Biology, Belgium

"Creating an immunostimulating tumor microenvironment: From vessel pruning to vessel tuning"

12:35

POSTER SPOTLIGHTS

Three top-scoring abstracts presented in 3 minute 'flash talks'

12:45

INDUSTRY SYMPOSIUM - 10x Genomics

Hannes Arnold 10x Genomics

"Profiling the Tumor Microenvironment: Functional Characterization at Single Cell Resolution and Spatial Gene Expression"

13:15

LUNCH

14:15

POSTER DISCUSSION SESSION 2

Tea/coffee available

Session 3 - Targeting Metastasis I

Chair: Sarah-Maria Fendt

15:45

Andreas Trumpp DKFZ, Germany

"Exploring CDK4/6 inhibitor drug resistance at the single cell level in metastatic breast cancer CTCs"

16:15

Gopalakrishnan Ramakrishnan UIC, USA

Proffered Paper 4: "The AMP activated protein kinase promotes metastasis through the regulation of ROS production"

16:30

Veronique Orian-Rousseau KIT, Germany

"Dual function of CD44 in cancer cells and in the tumor stroma"

17:00

Discussion Forum

Chaired by Caroline Dive, the panel of invited speakers will tackle this important question.

“To EMT or not to EMT, or anything in between?”

19:30

Conference dinner

Optional ticketed dinner beginning with a drinks reception in the Planck Lobby of Harnack House

08:30

POSTER VIEWING

Tea/coffee available

09:00

Meet the Expert talk

Andreas Trumpp DKFZ, Germany

Session 4 - Targeting Metastasis II

Chair: Jonathan Sleeman

09:30

Janine Erler University of Copenhagen, Denmark

"ECM remodelling during cancer progression"

10:00

Karen Vousden The Francis Crick Institute, UK

"A role for ROS in regulating metastasis"

10:30

COFFEE BREAK

Trade exhibition closes at 11:00

11:00

Emma Nolan The Francis Crick Institute, UK

Proffered Paper 5: "Lung exposure to ionizing radiation elicits neutrophil-mediated tissue perturbations and creates a pro-metastatic microenvironment"

11:15

Thordur Oskarsson DKFZ, Germany

"Regulation of the metastatic niche in breast cancer"

11:45

Keynote Lecture

Patricia Steeg NCI/NIH, USA

"The Blood-Tumor Barrier of Brain Metastases"

12:30

CLOSING SUMMARY & AWARDS CEREMONY

Scientific Programme Committee

12:40

BEUG FOUNDATION METASTASIS PRIZE

12:55

LUNCH & DEPART

Key dates

Bursary application deadline:
31 July 2019

Abstract submission deadline:
31 July 2019

Registration deadline:
06 September 2019

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