Amsterdam, Netherlands : 13 - 16 March 2017
Click here to download the Full Programme and Abstract Book for the conference.
Registration
Rode Hoed foyer
until 13:00
Welcome Lunch & Opening of the Trade Exhibition
Rode Hoed foyer & Oosterhuiszaal
Conference Welcome
Daniel Peeper
Chair of the Scientific Programme Committee
Keynote Lecture
Chair: Daniel Peeper
Caroline Dive CRUK Manchester Institute, UK
"Liquid biopsies: now and next"
Session 1: Tumour Evolution
Chair: Margaret Frame
Zlatko Trajanoski Innsbruck Medical University, Austria
"Immunoediting of the cancer genome during tumor progression and checkpoint blockade"
Julia Boshuizen NKI, Netherlands
Proffered Paper 1: "Early elimination of invasive and multidrug-resistant melanoma by a novel anti-AXL antibody drug conjugate"
COFFEE BREAK
Rode Hoed foyer
Keynote Lecture
Chair: Daniel Peeper
Jeffrey Engelman Novartis Institutes for BioMedical Research, USA
'Targeted therapies and resistance: where are we going?'
Session 2: Organoids, PDX, CTX, ODX
Chair: Joan Seoane
Meritxell Huch Gurdon Institute, UK
"Liver organoids for the study of liver biology and disease"
Nicholas Younger MRC Institute of Genetics & Molecular Medicine, UK
Proffered Paper 2: "A Combined Computational and Organoid-based Genetic Screening Strategy for the Identification of Novel Drivers of Intrahepatic Cholangiocarcinoma"
Emile Voest NKI, Netherlands
"Tailoring treatment to the individual patient with metastatic cancer using patient-derived tumor organoids, the TUMOROID and SENSOR initiatives"
NETWORKING RECEPTION
Oosterhuiszaal bar & Rode Hoed foyer
with hot buffet dinner
Keynote Lecture
Chair: Emile Voest
Hans Clevers Hubrecht Institute, Netherlands
"Lgr5 Stem Cell-based organoids in human disease"
POSTER VIEWING
Lower balcony
coffee available to purchase from the bar
Session 3: Metabolome Targets
Chair: Maria Sibilia
Ayelet Erez Weizmann Institute of Science, Israel
"The contribution of aminoacids' metabolism to carcinogenesis"
Eyal Gottlieb Technion Integrated Cancer Center, Israel
"The onco-metabolic role and liabilities of the TCA cycle in cancer"
Deepti Mathur Mount Sinai, USA
Proffered Paper 3: "PTEN inactivation creates vulnerability to DHODH inhibition"
COFFEE BREAK
Rode Hoed foyer
Session 4: Influence of the microenvironment
Chair: Caroline Dive
Margaret Frame Edinburgh CRC, UK
"Cancer cell polarization and immune evasion in the niche; co-regulation by the multitasking Focal Adhesion Kinase"
Jorrit Enserink Oslo University Hospital, Norway
Proffered Paper 4: "HSP90 Inhibitors Selectively Target FLT3-ITD-driven Acute Myeloid Leukemia and Bypass TKI Resistance"
Maria Sibilia Medical University of Vienna, Austria
"Cell-specific functions of the EGFR in tumor development"
Bart Vanhaesebroeck UCL, UK
"Targeting PI 3-kinase delta in haematological malignancies and solid tumours"
LUNCH & TRADE EXHIBITION
Rode Hoed foyer
Satellite Symposium - Elite Sponsor
Lecture hall
POSTER DEFENCE SESSION 1
Lower balcony
Coffee will be served at 15:00
Session 5: New Targets
Chair: Emile Voest
Richard Marais CRUK Manchester Institute, UK
"Precision medicine for melanoma: are we there yet?"
Joan Seoane Vall d'Hebron Institute of Oncology (VHIO), Spain
"Tumor microenvironment as a therapeutic target in glioblastoma"
Elisabeth Chen Sanger Institute, UK
Proffered Paper 5: "An apoptotic priming assay identifies signatures of apoptotic sensitivity and drug response in colorectal cancer cells"
Lars Zender University Hospital Tübingen, Germany
"In vivo RNAi technology and innovative cancer mouse models for accelerated target discovery"
POSTER VIEWING
Lower balcony
coffee available to purchase from the bar
Session 6: Combinatorial targeted & immuno approaches
Chair: Richard Marais
Elena Galvani CRUK Manchester Institute, UK
Proffered Paper 6: "Tumour mutational load does not correlate with response to anti-PD-1 treatment in a mouse model of melanoma"
Christian Blank NKI, Netherlands
"Combining targeted and immunotherapy in melanoma – why intermittent combination might be the way to go"
COFFEE BREAK
Rode Hoed foyer
Daniel Peeper NKI, Netherlands
"Systematic genetic perturbations to reveal therapeutic melanoma vulnerabilities"
Roger Lo UCLA, USA
"Therapeutic Resistance to MAPK and PD-1 Targeting"
LUNCH & TRADE EXHIBITION
Rode Hoed foyer
Satellite Symposium 2 - Elite Sponsor
Lecture hall
POSTER DEFENCE SESSION 2
Lower balcony
Round Table Discussions
coffee served at 14:30, session ends at 16:00
This session enables participants and speakers to converse informally in smaller groups. Participants are free to ask any questions they like and to move freely between the tables of different speakers.
CONFERENCE DINNER
Restaurant-Café In De Waag
Pre-booked optional extra
Last chance to view posters
Lower balcony
coffee available to purchase from the bar
Meet the Expert session
Chair: Daniel Peeper
Nuria Lopez-Bigas IRB Barcelona, Spain
Nuria, a biomedical informatics expert, will share from her personal perspective and experiences. There will an opportunity to ask your questions.
Session 7: Implementing Genomics into Clinical Practice
Chair: Lars Zender
Jos Jonkers NKI, Netherlands
"Determinants of therapy response and resistance in BRCA-deficient breast cancer"
COFFEE BREAK
Rode Hoed foyer
João Neto NKI, Netherlands
Proffered Paper 7: "Quadruple vertical targeting of an oncogenic pathway as a treatment strategy to prevent drug resistance"
Giorgio Stanta University of Trieste, Italy
"Research in patients' biological material as today's integral part of clinical activity"
Closing summary
Scientific Programme Committee
Poster Prizes and Meeting Bursaries will be presented by Giorgio Stanta
LUNCH AND DEPART
Rode Hoed foyer
Travel Grant application deadline:
20 January 2017
Abstract submission deadline:
20 January 2017
Registration and Payment deadline:
07 March 2017
"It is the best conference that I have ever experienced! A small scale conference where interactions with scientific experts are not restricted."
"Incredibly easy access to high impact researchers/speakers, all in a very friendly atmosphere."
Feedback from participants in the 2015 edition
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