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Novel biotherapies, specific kinase inhibitors and immunomodulatory antibodies have revolutionized the treatment of cancer, autoimmunity, and infectious diseases. This new era of molecular medicine has become possible thanks to major advances in immunology. The focus of this International Symposium on Immune Responses in Cancer and Infection is therefore to highlight recent progress in immunology, from the early steps of the immune response to the late regulation of inflammation and T and B cell responses in the settings of infection and cancer. The symposium will also cover innate sensing, immune checkpoints, and effector mechanisms. New technologies including genome editing, exome sequencing and live cell imaging will be highlighted during the program as their use has been a major contributory factor to recent advances. How the current understanding of immune mechanisms might enable the development of next-generation vaccines or curative therapies for patients with cancer or infections will be an over-arching theme of this first international symposium.