Application deadline: 31 Aug 2026
Institute: Karolinska Institutet
Country: Sweden
More information: https://ki.varbi.com/what:job/jobID:951539/
The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet (KI) is inviting applications for a postdoctoral researcher to join the Marie Arsenian-Henriksson research group in Stockholm, Sweden. The MTC department is internationally recognized for its multidisciplinary research in immunology, infection biology, cell biology, and cancer, with a strong emphasis on national and international collaboration.
The Arsenian-Henriksson laboratory investigates the MYC family of oncoproteins and their roles in tumorigenesis, metabolism, differentiation, and apoptosis across multiple cancer types. The group is a dynamic, multicultural research environment with extensive collaborations worldwide, providing an excellent setting for ambitious early-career researchers.
The successful candidate will contribute to projects focused on understanding how MYC drives metabolic reprogramming in childhood cancers, particularly neuroblastoma and medulloblastoma, with the goal of identifying novel metabolic vulnerabilities for therapeutic intervention. A second major research direction aims to develop MYC-based strategies to induce differentiation in aggressive neuroblastoma. The postdoctoral researcher will take a leading role in experimental design, execution, data analysis, visualization, publication of findings, and is also expected to contribute to grant writing and supervision of undergraduate and master's students.
Applicants should hold a PhD in Biomedical Science (or an equivalent degree) with a strong background in cancer biology. The position requires expertise in molecular and cellular biology techniques, including advanced cell culture, drug testing, immunofluorescence, PCR, Western blotting, imaging, metabolic profiling, lipidomics, proteomics, RNA sequencing sample preparation, basic omics analysis, lentiviral transduction, mouse models, immunohistochemistry, and scientific figure preparation. Experience in tumor metabolism, cancer differentiation, or therapeutic target identification is essential, while prior work on MYC, neuroblastoma, or medulloblastoma is considered an advantage. Candidates should demonstrate scientific independence, a collaborative approach, excellent communication skills, and fluency in English.
The position is offered as a postdoctoral scholarship intended for international researchers relocating to Sweden for postdoctoral training. Applicants must meet Karolinska Institutet's eligibility criteria for international postdoctoral scholarships, including holding a doctoral degree and not having completed their academic education in Sweden. Scholarships are awarded for a maximum of two years within four years of obtaining a doctoral degree.
Karolinska Institutet offers an outstanding research environment, consistently ranked among the world's leading medical universities. Researchers benefit from cutting-edge infrastructure, broad interdisciplinary expertise, close integration with healthcare, extensive collaborative opportunities, and access to modern campus facilities, including fitness and wellness resources. This position provides an exciting opportunity to contribute to translational cancer research with the potential to advance new therapeutic approaches for childhood cancers while developing an independent academic research profile.
