TissueGnostics

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Wednesday 17 February 17:00-17:05 CET
Speaker: Alexander Barang, TissueGnostics
"Contextual tissue symetry with AI - Immunophenotyping and Quantifying the Tumor Microenvironment in-situ"

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TissueGnostics is an Austrian Company, which provides fully integrated cutting-edge tissue cytometers, called TissueFAXS platform, for the scanning and the follow-up quantitative analysis of IHC/IF processed tissues, tissue microarrays (TMAs), cytospins, smears on slides as well as cultured cells in well plates or cell culture flasks. Our fully automated tissue cytometers are available in multiple configurations for brightfield-, fluorescence-, multispectral-, confocal- as well as high-throughput whole slide imaging (WSI) and include solutions for biomedical image analysis and quantitative pathology.

TissueFAXS systems are modular and upgradable. Every system is either in an upright configuration for scanning slides only, or inverted for scanning slides and cultured cells in well plates or cell culture flasks. Each system comes with an 8-slide stage, or a high-throughput automatic 120 slide loading system (only available for the upright configuration) and contains solutions for high-end quantitative image analysis (HistoQuest, TissueQuest and/or StrataQuest) which can address unlimited analysis requests such as:

• Immunophenotyping – determine the immune status of organs/tissues in-situ (tumor biology, autoimmune disorders, allergies, transplantation immunology, etc.)
• Tumor- & cellular- microenvironment – perform phenotypic and functional characterization of cellular sub-populations in spatial context
• Identification of single cells even in dense tissue (e.g. lymphatic organs) through Deep Learning algorithms
• Automated classification of tissue structures by Machine Learning into any number of classes per sample
• Multiplexing and spectral unmixing to perform high-plex assays on histological sections with single-cell precision
• Structural analysis and determination of subcellular marker localization
• Molecular single-cell profiling using antibody labeling, FISH, CISH, RNA-ISH, RNAscope, expansion microscopy – virtually any staining technique that can be visualized 
• Quantification of cellular pathogens, including intracellular parasites (e.g. leishmania) and viral load (e.g. SARS-CoV-2, Influenza, HIV, Zika, Dengue, Hepatitis, HSV, Chikungunya)
• Panoramic imaging and quantitative histopathology of over-sized slides

Video

Resources:

• TissueFAXS Q platform – experience high-resolution imaging
• Single-cell and contextual image analysis solutions with integrated AI modules
• StrataFAXS II – the compact brightfield tissue cytometer
• TissueFAXS Spectra – whole slide multispectral imaging

Any questions? Contact:

Dr. Rupert Ecker
CEO
rupert.ecker@tissuegnostics.com
 

Alex Barang
International Sales & Business Development
alex.barang@tissuegnostics.com
 

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