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Image of the Month: March 2017

The EACR Image of the Month highlights both scientifically and visually stimulating cancer research images from EACR members.

We are pleased to announce our March 2017 Image of the Month winner: our congratulations go to Florry Vyth-Dreese for sending this vibrant image of immune cells, macrophages and dendritic cells, in a lymph node follicle of a kidney cancer patient.

We wish to thank our panel of reviewers for their help in selecting the winning image.

Are you an EACR member? Do you have a scientific image you’d like to share? Please visit our Image of the Month page to find out how to submit your image.


Winner: Starry Sky - Macrophages and dendritic cells in lymph node follicle of a renal cancer patient.

The image depicts immune cells, macrophages and dendritic cells, in a lymph node follicle of a kidney cancer patient. The image originated from a study in which cancer and lymphoid tissues were investigated in detail using three colour immunofluorescence and confocal laser scanning microscopy for the presence of various immune cells. In this case, macrophages and dendritic cells both of which express HLA-DR (red). Strong expression of s100 (blue) is a marker of dendritic cells. IDO (Indoleamine 2, 3-dioxygenase, green), which depletes tryptophan thereby inhibiting proliferation of T cells, can be seen on both DC’s and macrophages. Original magnification x400.

Transformation to bright expression of colour markers was performed to accentuate the aesthetic characteristics of the picture.

The photograph is one of a collection of artistic images of the immuno-art project. This project has been set up by Florry Vyth-Dreese to raise funds for improving immunotherapeutic research and treatment. To this end, microscopic images were transformed into large and colourful artworks. People interested to obtain an artwork can mail and donate to this crowd funding project via the website www.immuno-art.nl.

Submitted by: Florry Vyth-Dreese, PhD, formerly Netherlands Cancer Institute, Amsterdam, Netherlands

06 Mar 2017

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