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EACR Member: Isabel Quiros Gonzales, University of Oviedo
"Effect of neuroendocrine plasticity in prostate cancer cells upon tumour microenvironment."
Dr. Quiros-Gonzalez's work focuses on the effects of neuroendocrine differentiation on tumour cell plasticity. By using highly-multiplexed immunohistochemistry they are planning on exploring the tumor microenvironment in neuroendocrine-differentiated tumours. They will compare the different compartments (immune, vascular, and stroma) where tumours are not present in order to understand the effects of neuroendocrine cells in the tumour microenvironment.
Maria Semitekolou, Biomedical Research Foundation of the Academy of Athens
"Dissecting the complexity of non-small cell lung cancer lesions by performing a multiscale immune profiling strategy."
Dr. Semitekolou's work focuses on mapping the cells that infiltrate the lung tumor microenvironment in order to map for cell subsets that are responsible for tumor recognition and control. By using a multimodal immune profiling strategy that comprehends scRNAseq, CyTOF and now highly multiplexed IHC, they want to identify the distinct immune cell compartments that reside in the tumor site and periphery of different non-small cell lung cancer patients, in an attempt to uncover novel predictive biomarkers using non-invasive strategies.
The prize winners will have the chance to stain their samples with the Maxpar® Human Immuno-Oncology IMC Panel Kit and 5 extra antibodies of their choice, which will then be run on a Hyperion Imaging System. This high-plex imaging approach will allow them to uncover new spatial biology insights.
We received many outstanding applications and appreciate the time and effort that went into these.
Find out more about Fluidigm (now Standard BioTools)
Application deadline: 27 May 2022
The European Association for Cancer Research (EACR) and Fluidigm are accepting immuno-oncology research proposals involving Imaging Mass Cytometry™ (IMC™) to gain a deeper understanding of the intricacies of the immune and tumor microenvironment. Grants will be awarded to the two most impactful proposals focusing on any type of cancer.
The award is open to EACR members and non-members. One of the two grants will be awarded to a current EACR member. If a non-member is granted the second award, that researcher will receive a one-year EACR membership, paid in full by Fluidigm.
If you have any questions or need some support with your application, please contact marketing-europe@fluidigm.com. For full terms and conditions please visit the award webpage. The closing date for submissions is 23:59 BST on May 27 2022.