Registration

Planck Lobby

Coffee and tea will be available

Welcome and introduction

Scientific Programme Committee

Keynote Lecture 1

Akira Yasui Tohoku University, Japan

"Histone modification and nucleosome remodeling regulating transcription and DNA repair"

Speed Networking

Planck Lobby

Welcome buffet

Meitner Saal

Trade exhibition opens

Poster Preview

Meitner Saal

Coffee and tea will be available.

Session 1: Chromatin remodelers and DNA damage

Chair: Susan Gasser

Claudia Lukas NNF CPR, Denmark

"The role of DNA replication stress in cell fate decisions after whole-genome duplication"

Niels Mailand NNF CPR, Denmark

"Regulation of chromatin ubiquitylation in the DNA damage response"

Aaron Goodarzi University of Calgary, Canada

Proffered Paper 1: "The CHD6 chromatin remodeler is an oxidative stress-induced DNA damage response factor"

Exhibitor Introductions

A fun session to introduce the companies who are exhibiting at the conference.

COFFEE BREAK & TRADE EXHIBITION

Meitner Saal

Boris Pfander Max Planck Institute of Biochemistry, Germany

Proffered Paper 2: "Chromatin constitutes a bottleneck in the response to double strand breaks"

Jessica Downs ICR, UK

"The PBAF chromatin remodelling complex and maintenance of genome stability"

Satellite Symposium: Chromatrap

Lunch

Liebig Vault Restaurant

Hot buffet lunch with seating available

POSTER DEFENCE SESSION 1 & TRADE EXHIBITION

Meitner Saal

Odd numbered posters (1,3,5 etc) will be presented in this session.

Session 2: Propagating the epigenome

Chair: Jo Morris

Iestyn Whitehouse MSKCC, USA

"Coupling of genes and replication origins"

Christopher Douse University of Cambridge, UK

Proffered Paper: "Molecular mechanisms of transgene silencing by the Human Silencing Hub (HUSH) and MORC2"

Kyle Miller University of Texas at Austin, USA

Proffered Paper 3: "Bromodomain proteins: Readers of Genome Integrity"

Kristijan Ramadan University of Oxford, UK

"Ubiqutin dependent ATPase p97 and deubiquitinating enzyme X (DUBX) regulate DNA damage response after ionising radiation"

Round Table Discussions

Einstein Lounge

Beverages are available to purchase from the bar.

Free evening to explore Berlin

Poster Preview

Meitner Saal

Coffee and tea will be available.

Meet the Expert

Penny Jeggo University of Sussex, UK

An interactive session where Prof. Jeggo will share from her personal perspective and experiences. There will be a chance to ask your questions.

Session 3: DNA damage repair

Chair: Iestyn Whitehouse

Haico van Attikum LUMC, Netherlands

"Regulation and dynamics of DNA repair in a chromatin context"

Jacques Cote Université Laval, Canada

Proffered Paper 4: "Phospho-dependent recruitment of NuA4 by MRX at DNA breaks regulates RPA dynamics during resection"

Ulrich Rass Friedrich Miescher Institute, Switzerland

Proffered Paper 5: "Helicases and nucleases determining replication fork recovery or demise, and implications for genome stability and human disease"

COFFEE BREAK & TRADE EXHIBITION

Meitner Saal

Brendan Price Dana-Farber Cancer Institute, USA

"Constructing specialized, acetylated chromatin domains to promote DSB repair"

Jo Morris University of Birmingham, UK

"The SUMO bomb in DNA double-strand break repair"

Amélie Fradet-Turcotte Université Laval, Canada

Proffered Paper 6: "A new class of ubiquitylated-histone readers involved in the response to DNA damage"

Lunch

Liebig Vault Restaurant

Hot buffet lunch with seating available

POSTER DEFENCE SESSION 2 & TRADE EXHIBITION

Meitner Saal

Even numbered posters (2,4,6 etc) will be presented in this session.

Session 4: Chromatin and disease states

Chair: Penny Jeggo

Tim Humphrey University of Oxford, UK

"Histone H3K36 trimethylation, genome stability and cancer"

Ashby Morrison Stanford University, USA

Proffered Paper 7: "Carcinogen susceptibility is regulated by genome architecture and predicts cancer mutagenesis"

Fabrizio d'Adda di Fagagna IFOM, Italy

"DNA damage response activation in cancer and the role of non coding RNAs"

Keynote Lecture 2

Geneviève Almouzni Institute Curie, France

"Shaping chromatin in the nucleus, the bricks and the architects"

Drinks Reception & Conference Dinner

Join us for a drink in the Planck Lobby, followed by the Conference Dinner in Liebig Vault. This is an optional event with a limited number of tickets available.

Session 5: Chromatin remodelers at the transcription / replication interface

Chair: Jessica Downs

Manolis Papamichos-Chronakis Newcastle University, UK

"INO80 chromatin remodeller links RNA quality control to transcriptional regulation"

Philipp Oberdoerffer National Cancer Institute, USA

"Replication stress in chromatin: getting fragile sites in shape"

Andrew Wood IGMM Edinburgh, UK

Proffered Paper 8: "Imprinted genes as a model system to study the impact of chromatin on targeted mutagenesis"

COFFEE BREAK

Meitner Saal

Sophie Polo Epigenetics and Cell Fate, France

Proffered Paper 9: "Epigenome maintenance in response to DNA damage"

Gaëlle Legube CBI Toulouse, France

"Chromatin and chromosome dynamics following DNA Double Strand Break"

The EMBO Keynote Lecture

Susan Gasser FMI, Switzerland

"Remodelers in response to DNA damage"

Closing Remarks & Presentation of Awards

Scientific Programme Committee

Lunch & depart

Planck Lobby

A packed lunch will be provided