EACR-OECI Molecular Pathology Approach to Cancer

Bergamo, Italy : 28 - 30 March 2023

Scientific Programme

Tuesday 28th March 2023

Listed times are in Central European Summer Time (CEST)

11:30

REGISTRATION & WELCOME LUNCH

Registration will open at 11:30am. The welcome lunch will be available from 12:00pm.

13:00

CONFERENCE WELCOME

Session 1: Perspectives of Artificial Intelligence in pathology 

Chair: Eli Pikarsky

13:10

Tuvik Beker Pangea Biomed, Israel

"ENLIGHT: Predicting response to cancer therapy based on gene expression patterns from RNAseq or H&E slides"

Q&A: 13:30-13:40

13:40

Mara Graziani (Virtual Presentation) IBM Research, Switzerland

"The human-AI horizon in microscopy imaging"

Q&A: 14:00-14:10

14:10

Zak Kinsella Royal College Of Surgeons, Ireland

Proffered Paper 1: "Investigating the landscape of early-stage estrogen receptor-positive breast cancer using digital image analysis"

Q&A: 14:20-14:25

14:25

EXHIBITOR INTRODUCTIONS

14:35

COFFEE BREAK & EXHIBITION

15:05

Sebastian Foersch University Medical Center Mainz, Germany

"From tissue morphology to genomic alterations – AI in precision tumor pathology"

Q&A: 15:25-15:35

15:35

Raza Ali Cancer Research UK Cambridge Institute, UK

"Highly multiplexed imaging for personalised breast immuno-oncology"

Q&A: 15:55-16:05

16:05

POSTER SPOTLIGHTS

3 top abstracts presented as 3-minute flash talks

16:15

INDUSTRY SYMPOSIUM - SeqOne Genomics

Marie-Pierre Wissler & Michael Blum Cypath & SeqOne Genomics

"NGS for precision medicine: interpretation of tumor variants and HRD biomarker"

16:45

Meet the Experts

Marjolijn Ligtenberg & Raza Ali

Prof. Dr. Ligtenberg & Dr Ali will host an informal session where they will both share their own personal and professional experiences of their paths to scientific leadership.

17:15

Welcome Reception

Drinks reception with buffet served from 17:30

18:15

POSTER DISCUSSION 1

Wednesday 29th March 2023

Listed times are in Central European Summer Time (CEST)

08:15

MORNING COFFEE & POSTER VIEWING

08:45

INDUSTRY SPOTLIGHT - Lunaphore Technologies

Cansaran Saygili Demir University of Bern, Switzerland

"Mapping the tumor budding and its microenvironment in colorectal cancer using hyperplex sequential immunofluorescence"

Session 2 - Spatial and longitudinal diagnostics to overcome tumor heterogeneity

Chair: Sabine Merkelbach-Bruse

09:00

Lukas Bubendorf University Hospital Basel, Switzerland

"Impact of tumor heterogeneity and evolution in NSCLC"

Q&A: 09:20-09:30

09:30

Anita Sveen Oslo University Hospital, Norway

Proffered Paper 2: "Multiregional molecular profiling of colorectal cancers defines prognostic features less vulnerable to tumor heterogeneity"

Q&A: 09:40-09:45

09:45

Ellen Heitzer Medical University of Graz, Austria

"Molecular profiling of solid tumors by ctDNA"

Q&A: 10:05-10:15

10:15

Ilse Rooman Vrije Universiteit Brussel, Belgium

Proffered Paper 3: "High resolution in situ analysis reveals phenotypic and functional diversification within single pancreatic tumour ducts"

Q&A: 10:25-10:30

10:30

COFFEE BREAK & EXHIBITION

11:00

Leeat Keren Weizmann Institute of Science, Israel

"Unraveling the tumor microenvironment using multiplexed imaging"

Q&A: 11:20-11:30

11:30

Marit Otterlei Fjørtoft Institute for Cancer Research, Norway

Proffered Paper 4: "Single cell analysis of paired lymph nodes and primary tumors in breast cancer patients"

Q&A: 11:40-11:45

11:45

POSTER SPOTLIGHTS

3 top abstracts presented as 3-minute flash talks

11:55

INDUSTRY SYMPOSIUM: Bio-Rad Laboratories

Sergio Marchini Milan IRCCS Humanitas Research Hospital, Italy

"Analysis of ctDNA to intercept the whispering voice of High Grade Serous Ovarian Cancer"

12:25

LUNCH

13:25

POSTER DISCUSSION SESSION 2

Session 3 - Next Generation Molecular Pathology

Chair: Giorgio Stanta

14:55

Giorgio Stanta OECI, Italy

"European Master in Molecular Pathology as Instrument of Molecular Pathology Normalization at European Level"

Q&A: 15:15-15:25

15:25

Hege Russnes Oslo University Hospital, Norway

"Comprehensive molecular profiling of Norwegian patients with advanced cancer - the impact on diagnosis and treatment opportunities."

Q&A: 15:45-15:55

15:55

Marjolijn Ligtenberg Radboud University Medical Center, Netherlands

"Molecular profiles of malignancies from patients with Lynch syndrome or hereditary breast and ovarian cancer"

Q&A: 16:15-16:25

16:25

COFFEE BREAK & EXHIBITION

16:55

Kushtrim Kryeziu Institute for Cancer Research, OUH, Norway

Proffered Paper 5: "Immunohistopathology of organoids derived from multifocal colorectal cancer liver metastases"

Q&A: 17:05-17:10

17:10

Olli Carpen University of Helsinki, Finland

"Identifying critical outcome-regulating elements in ovarian cancer by tissue image analysis combined with spatial transcriptomics"

Q&A: 17:30-17:40

17:40

Panel Discussion

Chaired by Eli Pikarsky and Ragnhild Lothe

Unlocking the Potential of Molecular Pathology: Opportunities and Challenges Ahead

19:30

Conference Dinner

Optional ticketed dinner to be held at 'Taverna Valtellinese'

Thursday 30th March 2023

Listed times are in Central European Summer Time (CEST)

08:15

MORNING COFFEE & POSTER VIEWING

08:45

INDUSTRY SPOTLIGHT - TissueGnostics

Felicitas Mungenast, PhD

"Applications of Tissue Cytometry – Immunophenotyping, Spatial Analysis and Tissue Classification"

Session 4 - Comprehensive cancer profiling in clinical diagnostics

Chair: Luigi Terracciano

09:00

Sabine Merkelbach-Bruse University Hospital Cologne, Germany

"Homologous recombination deficiency – causes, effects and detection methods"

Q&A: 09:20-09:30

09:30

Luigi Terracciano University Hospital Basel, Switzerland

"Precision medicine in liver cancer: reducing the gap between bench and bedside"

Q&A: 09:50-10:00

10:00

COFFEE BREAK & EXHIBITION

10:30

Eli Pikarsky The Hebrew University of Jerusalem, Israel

"Establishing an In House Genomic Testing Facility – Opportunities and Hurdles"

Q&A: 10:50-11:00

11:00

Remco van Cruchten Radboudumc, Netherlands

Proffered Paper 6: "Molecular tumor profiling using a custom WES-based method for FFPE-material"

Q&A: 11:10-11:15

11:15

CLOSING KEYNOTE LECTURE

Judith V.M.G. Bovee Leiden University Medical Center, Netherlands

"Disentangling molecular mechanisms in sarcomas; making sense of a heterogeneous group of rare cancers"

Q&A: 11:45-12:00

12:00

SUMMARY & AWARDS

12:15

DEPART

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