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REGISTRATION & WELCOME LUNCH (lunch from 12:00)

WELCOME TO DAY ONE

SESSION 1: Integrative Liquid Biopsies

Chair: Nicola Aceto

Ellen Heitzer Medical University of Graz, Graz, Austria

'The liquid biopsy research of Professor Michael Speicher'

Francesca Demichelis University of Trento, Trento, Italy

'The added value of multi-modal liquid biopsy approaches for cancer profiling'

Q&A 14:00 - 14:10

Carolin Sauer EMBL-EBI, Cambridge, UK

Proffered Paper 1: 'Multimodal liquid biopsy analysis in children with cancer on a national scale using long-read sequencing'

Q&A 14:20 - 14:25

EXHIBITOR INTRODUCTIONS

COFFEE BREAK, EXHIBITION & SOLO TRAVELLERS' MEET-UP

James Hadfield Oncology Translational Medicine at AstraZeneca, Cambridge, UK

'ctDNA for MRD and a pathway to cure'

Q&A 15:35 - 15:45

Manuel Valiente CNIO, Madrid, Spain

'Biomarkers of therapeutic response in brain metastasis '

Q&A 16:05 - 16:15

POSTER SPOTLIGHTS

INDUSTRY SYMPOSIUM - Thermo Fisher Scientific

Dr Maria Arechederra and Dr Carmen Berasain Cancer Center Clínica Universidad de Navarra (CCUN)

'Next-generation sequencing of bile cell-free DNA for the early detection of malignant biliary strictures'

MEET THE EXPERT

An Hendrix, Ghent University, Belgium; Valsamo Anagnostou, Johns Hopkins University School of Medicine, USA; Shang Cai, Westlake University, Hangzou, China

WELCOME RECEPTION

POSTER DISCUSSION SESSION 1

EARLY POSTER VIEWING with coffee

INDUSTRY SPOTLIGHT - Menarini Silicon Biosystems

Francesca Fontana Menarini Silicon Biosystems

'Technologies for cell-based liquid biopsy'

SESSION 2: Circulating tumour cells

Chair: Caroline Dive

Johann De Bono ICR, London, UK

'Integrative analyses of liquid biopsies in advanced prostate cancer care'

Q&A 09:20 - 09:30

Joao Miguel Fernandes Alves Universidad de Vigo, Vigo, Spain

Proffered Paper 2: 'CTC genomic heterogeneity predicts survival in metastatic colorectal cancer patients'

Shang Cai Westlake University, Hangzou, China

'Cytosolic Bacteria in Tumor Cells Promote Immune Evasion during Breast Cancer Metastatic Recurrence'

Q&A 10:05 - 10:15

Nicola Aceto ETH Zurich, Zurich, Switzerland

'Circulating tumour cell clusters'

Q&A 10:35 - 10:45

COFFEE BREAK & EXHIBITION

Coffee break sponsored by Tecan Trading

Huiping Liu Northwestern University, Chicago, USA

'Plasticity of circulating tumor cell clusters in response to therapy'

Q&A 11:35 - 11:45

Rui Neves UniKlinik Dusseldorf, Dusseldorf, Germany

Proffered Paper 3: 'Phenotypic diversity of CTCs and tdEVs in tumour-draining veins is linked to poor prognosis in colorectal cancer'

POSTER SPOTLIGHTS

INDUSTRY SYMPOSIUM - biomodal

Alexandra Clipson Cancer Research UK National Biomarker Centre

'Harnessing the full potential of cfDNA through multi-omic analysis'

LUNCH

POSTER DISCUSSION SESSION 2

SESSION 3: Discovery in liquid biopsy and new technologies

Chair: Florent Mouliere

An Hendrix Ghent Universiteit, Ghent, Belgium

'Extracellular vesicle-based biomarkers: from technology towards biomedical application'

Q&A 15:30 - 15:40

Bogdan Mateescu University of Zurich, Zurich, Switzerland

Proffered Paper 4: 'Beyond cfDNA: Exploring the Regulatory Landscape of Cell-Free RNA in liquid biopsy via RNA-Binding Proteins’

Q&A 15:50 - 15:55

Virginie Marcel Cancer Research Center Lyon, Lyon, France

Proffered Paper 5: 'A distinct circulating snoRNA signature identifies bone recurrence in breast cancer patients compared to other metastatic sites'

Q&A 16:05 - 16:10

Cristina Saura Manich Vall d'Hebron, Barcelona, Spain

'Breast Milk Liquid Biopsy for Early Detection of Breast Cancer in Postpartum Women'

Q&A 16:30 - 16:40

COFFEE BREAK & EXHIBITION

THE EMBO KEYNOTE LECTURE

Mathias Uhlen KTH Royal Institute of Technology, Stockholm, Sweden

'A human pan-disease blood atlas based on next generation blood profiling'

Q&A 17:30 - 17:40

Joshua Edel Imperial College London, London, UK

'Novel diagnostic approach for highly multiplexed biomarker detection'

Q&A 18:00 - 18:10

DISCUSSION PANEL

Caroline Dive, CRUK, Manchester, UK; Ellen Heitzer, Medical University of Graz, Graz, Austria; Nicola Aceto, ETH Zurich, Zurich, Switzerland; Florent Mouliere, CRUK, Manchester, UK

CONFERENCE DINNER

The Conference Dinner will be held at the atmospheric La Maison Restaurant, Optional ticketed event.

EARLY POSTER VIEWING with coffee

INDUSTRY SPOTLIGHT - Illumina

Dr Anna Babayan Illumina

'Enabling multiomic approach in liquid biopsy research'

SESSION 4: Implementation of liquid biopsy and clinical trials

Chair: Ellen Heitzer

Eleni Tomazou St Anna CCRI, Vienna, Austria

'Integration of cfDNA methylation and fragmentation patterns through deep learning'

Q&A 09:20 - 09:30

Joshua Lang Carbone Cancer Centre, University of Wisconsin, Madison, USA

'From Prognostic to Predictive: Multiplexed Liquid Biopsies in Metastatic Prostate Cancer'

Q&A 09:50 - 10:00

Katharina Jonas Medical University of Graz, Graz, Austria

Proffered Paper 6: 'Low-level variants present a challenge in the clinical interpretation of liquid-biopsy-based comprehensive genomic profiling for patients with solid tumors'

Q&A 10:10 - 10:15

COFFEE BREAK & EXHIBITION

Florent Mouliere CRUK, Manchester, UK

'Cancer detection and monitoring using multi-modal liquid biopsy.'

Q&A 11:05 - 11:15

Closing Keynote Lecture

Valsamo Anagnostou Johns Hopkins University School of Medicine, Baltimore, USA

'Liquid biopsy approaches for cancer characterization and monitoring'

Q&A 11:45 - 12:00

SUMMARY AWARDS & CLOSE