Bergamo, Italy : 24 - 26 May 2022
Registration & Welcome Lunch
Conference Welcome
Scientific Programme Committee
SESSION 1: Circulating Tumor DNA
Chair: Alberto Bardelli
Keynote Lecture
Dan Landau New York Genome Center, USA
"Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring"
Q&A: 13:40 - 13:55
Nitzan Rosenfeld CRUK Cambridge Institute, UK
“Expanding roles of liquid biopsies for cancer diagnostics”
Q&A: 14:15 - 14:25
Angela An University of Cambridge, UK
Proffered Paper 1: "Detecting ctDNA in dried blood spots from patients with advanced cancer and xenograft mouse models"
Q&A: 14:35 - 14:40
Exhibitor Introductions
60-second intro pitches by each company
Coffee Break & Exhibition
SESSION 2: Predicting immunotherapy responses
Chair: Alberto Bardelli
Luis Diaz MSKCC, USA (Presenting Remotely)
Q&A: 15:40 - 15:50
Sara Valpione Cancer Research MI, UK
"Liquid biopsies to investigate T cell dynamics during immunotherapy"
Q&A: 16:10 - 16:20
Poster Spotlights
3 top abstracts presented as 3 minute flash talks
Discussion Forum
“Alternatives to blood for liquid biopsy”
Welcome Reception
including drinks and light food
Poster Discussion Session 1 (Posters 1 - 55)
until 19:45
Poster Viewing - coffee and biscuits
Posters may be freely browsed
SESSION 3: Circulating tumor cells
Chair: Evi Lianidou
Industry Spotlight - Precision For Medicine
Darren Davis Precision For Medicine
“Using Circulating Tumor Cells as Pharmacodynamic Biomarkers in Clinical Trials”
Q&A: 09:20 - 09:30
Haichao Wang University of Cambridge, UK
Proffered Paper 2: "cfDNAPro: an R/Bioconductor package to characterise and visualise cell-free DNA biological features in liquid biopsy"
Q&A: 09:40 - 09:45
The EMBO Keynote Lecture
Caroline Dive CRUK Manchester Institute, UK
"Circulating Tumour Cells in Lung Cancer"
Q&A: 10:05 - 10:15
Claus Jørgensen CRUK Manchester Institute, UK
“The phenotypic landscape of circulating tumour cells in pancreatic ductal adenocarcinoma patients”
Q&A: 10:35 - 10:45
Coffee Break & Exhibition
Nicola Aceto ETH Zurich, Switzerland
“Biology and vulnerabilities of circulating tumor cell clusters”
Q&A: 11:35 - 11:45
Francesco Gatto Elypta, Sweden
Proffered Paper 3: "Multi-cancer early detection using non-invasive profiling of free glycosaminoglycans as biomarkers of tumor metabolism"
Q&A: 11:55 - 12:00
Poster Spotlights
3 top abstracts presented as 3 minute flash talks
Industry Symposium - Thermo Fisher Scientific
David Guttery
"Verification of an NGS approach for earlier detection of endometrial cancer relapse using liquid biopsies"
Lunch & Exhibition
Poster Discussion Session 2 (Posters 56 - 108)
Milana Frenkel-Morgenstern Bar-Ilan University, Israel
"Liquid Biopsy using gene-gene fusions in Complex Diseases"
Q&A: 15:25 - 15:35
Daniel Haber Harvard Medical School, USA (Presenting remotely)
"Functional Annotation of Circulating Tumor Cells"
Q&A: 15:55 - 16:05
Roni Ben Ami The Hebrew University of Jerusalem, Israel
Proffered Paper 4: "Protein biomarkers and alternatively methylated cell-free DNA for detection of early-stage pancreatic cancer"
Q&A: 16:15 - 16:20
Efrat Shema Weizmann Institute of Science, Israel
Proffered Paper 5: "Multiplexed Single-Molecule Epigenetic Analysis of Plasma-Isolated Nucleosomes for Cancer Diagnostics"
Q&A: 16:30 - 16:35
Coffee Break & Exhibition
SESSION 4: ctDNA-MRD
Chair: Nickolas Papadopoulos
Ryan Corcoran Harvard Medical School, USA
“Clinical Applications of Liquid Biopsy to Detect Minimal Residual Disease”
Q&A: 17:25 - 17:35
Silvia Marsoni IFOM, Italy
"Interventional liquid biopsy in colorectal cancer"
Q&A: 17:55 - 18:05
Discussion Forum (40 minutes)
“Beyond ctDNA mutations, as a liquid biopsy for personalised cancer medicine”
Conference Dinner
Taverna Valtellinese
Optional ticketed dinner
Poster Viewing - coffee and biscuits
Posters may be freely browsed
Industry Spotlight - Novosanis
Amit Arora DNA Genotek
“Bridging the gap: moving urine as a liquid biopsy into clinical practice"
SESSION 5: CTDNA, Methylation & Fragmentomics
Chair: Caroline Dive
Dominic Rothwell CRUK Manchester Institute, UK
"Profiling of the cfDNA methylome for detection, monitoring and characterisation of cancer"
Q&A: 09:20 - 09:30
Sarah-Jane Dawson Peter Mac, Australia
“Genomic and Epigenomic Monitoring of Cancer Using Liquid Biopsies”
Q&A: 09:50 - 10:00
Coffee Break & Exhibition
Ellen Heitzer Medical University of Graz, Austria
"Genome-wide analysis of ctDNA for cancer monitoring and stratification"
Q&A: 10:50 - 11:00
Yari Ciani University of Trento, Italy
Proffered Paper 6: "Detection and tracking of breast cancer signal in the plasma of patients on neoadjuvant chemotherapy treatment via cfDNA and EV-RNA analysis"
Q&A: 11:10 - 11:15
Gabriella Sozzi Istituto Nazionale Tumori, Italy
"Liquid biopsy for screening and early detection of lung cancer"
Q&A: 11:35 - 11:45
Conference Summary & Depart