Bergamo, Italy : 15 - 17 May 2019
REGISTRATION
until 13:00
WELCOME LUNCH & TRADE EXHIBITION
CONFERENCE WELCOME
SESSION 1: Tracking Cancer and MRD Using Liquid Biopsies
Chair: Sarah-Jane Dawson
Opening Keynote
Nickolas Papadopoulos Johns Hopkins University, USA
"Non-invasive earlier detection of cancer"
Rebecca Lee CRUK Manchester Institute, UK
"Clinical application of circulating tumour DNA in melanoma"
Iñaki Comino-Mendez The Institute of Cancer Research London, UK
Proffered Paper 1: "Molecular Fingerprint Sequencing: ultra-sensitive assay for circulating-tumour DNA detection in early breast cancer"
EXHIBITOR INTRODUCTIONS
COFFEE BREAK & TRADE EXHIBITION
Alberto Bardelli University of Torino, Italy
"Tracking colorectal cancer evolution"
Alice Shaw Massachusetts General Hospital, USA
"Circulating tumor DNA and evolution of drug resistance in lung cancer"
Francesca Chemi CRUK Manchester Institute, UK
Proffered Paper 2: "Pulmonary venous tumour cells disseminating prior to tumour resection are heterogeneous, predict relapse and seed future metastasis: TRACERx Lung"
Joan Seoane Vall D'Hebron Institute of Oncology, Spain
"Liquid biopsies from brain tumours"
POSTER SPOTLIGHTS
Four top-scoring abstracts presented in 3 minute 'flash talks'
NETWORKING RECEPTION
including drinks and light food
POSTER DISCUSSION SESSION 1
Posters 1-53 will be presented until 19:30
POSTER VIEWING & TRADE EXHIBITION
Coffee / tea available
INDUSTRY SPOTLIGHT - HTG Molecular Diagnostics
until 08:55
Carlo Bottari HTG Molecular Diagnostics, France
"How extraction-free HTG EdgeSeq technology solves unmet needs in liquid biopsy molecular profiling"
SESSION 2: Blood-based Early Detection and Screening
Chair: Caroline Dive
The EMBO Keynote Lecture
Carlos Caldas CRUK Cambridge Institute, UK
"ctDNA in the management of cancer"
Anna Supernat Medical University of Gdańsk, Poland
Proffered Paper 3: "Tumor-Educated Platelet analysis enables discrimination between benign lesions and early stage ovarian cancer"
Alain Thierry IRCM, France
"Circulating DNA structural features as key parameters for cancer screening"
COFFEE BREAK & TRADE EXHIBITION
Weimin Ci Beijing Institute of Genomics, China
Proffered Paper 4: "GUdetector: detection and localization of genitourinary cancers based on copy-number profiling using shallow whole genome sequencing of urine cell-free DNA"
Allen Chan CUHK, Hong Kong
"Circulating DNA for cancer screening"
POSTER SPOTLIGHTS
Four top-scoring abstracts presented in 3 minute 'flash talks'
INDUSTRY SYMPOSIUM - Thermo Fisher Scientific
Ilaria Alborelli University Hospital Basel, Switzerland
“Plasma-based next-generation sequencing analysis of cancer-hotspot genomic alterations in non-small cell lung cancer”
LUNCH & TRADE EXHIBITION
POSTER DISCUSSION SESSION 2
Posters 54-106 will be presented
SESSION 3: Circulating Tumour Cells
Chair: Carlos Caldas
Caroline Dive CRUK Manchester Institute, UK
"Circulating Tumour Cells in lung cancer - lethal subclones and therapy testing 'avatars'"
Nicola Aceto University of Basel, Switzerland
"Features and vulnerabilities of circulating tumour cell clusters"
Carolina Reduzzi Istituto Nazionale Tumori, Italy
Proffered Paper 5: "Dual-positive cells circulating in the blood of cancer patients: tumor origin and clinical potential"
Evi Lianidou University of Athens, Greece
"Epigenetic alterations in CTCs and corresponding ctDNA"
COFFEE BREAK & TRADE EXHIBITION
Rui Neves UniKlinik Dusseldorf, Germany
Proffered Paper 6: "The molecular evolution of systemic metastatic castration resistant prostate cancer during therapy monitored by analysis of individual circulating tumour cells"
Klaus Pantel University Medical Centre Hamburg-Eppendorf, Germany
"Circulating Tumor Cells: biology and clinical applications as liquid biopsy"
PANEL DISCUSSION
Chaired by Sarah-Jane Dawson, the panel of invited speakers will tackle this important question.
"How do we move liquid biopsies from a research tool to part of routine decision making?"
Conference Dinner
Taverna Valtellinese
Optional ticketed dinner
POSTER VIEWING & TRADE EXHIBITION
Coffee / tea available
INDUSTRY SPOTLIGHT - VyCAP
until 08:55
Arjan Tibbe VyCAP, Netherlands
"Solution for single cell analysis, identification and isolation"
SESSION 4: Novel Cancer Biomarkers in Blood
Chair: Alberto Bardelli
Federica Di Nicolantonio Candiolo Cancer Institute, Italy
"Cancer epigenetic alterations in cell free DNA"
Gabriella Sozzi Istituto Nazionale Tumori, Italy
"Circulating miRNAs as biomarkers for early detection and therapeutics of lung cancer"
Ruben Van Paemel Ghent University, Belgium
Proffered Paper 7: "Non-invasive classification of pediatric tumor types using reduced representation bisulfite sequencing of cell-free DNA: a proof-of-principle study"
Michael Speicher Medical University of Graz, Austria
"Epigenetic traces in plasma DNA"
COFFEE BREAK & TRADE EXHIBITION
Naveen Ramesh MD Anderson Cancer Center, USA
Proffered Paper 8: "Delineating Clonal Evolution During Therapeutic Resistance in Prostate Cancer by Whole Genome Plasma Sequencing"
Sarah-Jane Dawson Peter McCallum Cancer Centre, Australia
"Translational and clinical applications of ctDNA in solid and haematological malignancies"
Johann de Bono The Institute of Cancer Research, UK
"Improving drug development with liquid biomarkers"
SUMMARY & AWARDS
LUNCH & DEPART