EACR-ESMO Joint Conference on Liquid Biopsies

Bergamo, Italy : 15 - 17 May 2019

Scientific Programme

Wednesday 15th May 2019

11:30

REGISTRATION

until 13:00

12:00

WELCOME LUNCH & TRADE EXHIBITION

13:00

CONFERENCE WELCOME

13:10

SESSION 1: Tracking Cancer and MRD Using Liquid Biopsies

Chair: Sarah-Jane Dawson

13:10

Opening Keynote

Nickolas Papadopoulos Johns Hopkins University, USA

"Non-invasive earlier detection of cancer"

13:55

Rebecca Lee CRUK Manchester Institute, UK

"Clinical application of circulating tumour DNA in melanoma"

14:25

Iñaki Comino-Mendez The Institute of Cancer Research London, UK

Proffered Paper 1: "Molecular Fingerprint Sequencing: ultra-sensitive assay for circulating-tumour DNA detection in early breast cancer"

14:40

EXHIBITOR INTRODUCTIONS

14:50

COFFEE BREAK & TRADE EXHIBITION

15:25

Alberto Bardelli University of Torino, Italy

"Tracking colorectal cancer evolution"

15:55

Alice Shaw Massachusetts General Hospital, USA

"Circulating tumor DNA and evolution of drug resistance in lung cancer"

16:25

Francesca Chemi CRUK Manchester Institute, UK

Proffered Paper 2: "Pulmonary venous tumour cells disseminating prior to tumour resection are heterogeneous, predict relapse and seed future metastasis: TRACERx Lung"

16:40

Joan Seoane Vall D'Hebron Institute of Oncology, Spain

"Liquid biopsies from brain tumours"

17:10

POSTER SPOTLIGHTS

Four top-scoring abstracts presented in 3 minute 'flash talks'

17:25

NETWORKING RECEPTION

including drinks and light food

18:00

POSTER DISCUSSION SESSION 1

Posters 1-53 will be presented until 19:30

Thursday 16th May 2019

08:30

POSTER VIEWING & TRADE EXHIBITION

Coffee / tea available

08:40

INDUSTRY SPOTLIGHT - HTG Molecular Diagnostics

until 08:55

Carlo Bottari HTG Molecular Diagnostics, France

"How extraction-free HTG EdgeSeq technology solves unmet needs in liquid biopsy molecular profiling"

09:00

SESSION 2: Blood-based Early Detection and Screening

Chair: Caroline Dive

09:00

The EMBO Keynote Lecture

Carlos Caldas CRUK Cambridge Institute, UK

"ctDNA in the management of cancer"

09:45

Anna Supernat Medical University of Gdańsk, Poland

Proffered Paper 3: "Tumor-Educated Platelet analysis enables discrimination between benign lesions and early stage ovarian cancer"

10:00

Alain Thierry IRCM, France

"Circulating DNA structural features as key parameters for cancer screening"

10:30

COFFEE BREAK & TRADE EXHIBITION

11:00

Weimin Ci Beijing Institute of Genomics, China

Proffered Paper 4: "GUdetector: detection and localization of genitourinary cancers based on copy-number profiling using shallow whole genome sequencing of urine cell-free DNA"

11:15

Allen Chan CUHK, Hong Kong

"Circulating DNA for cancer screening"

11:45

POSTER SPOTLIGHTS

Four top-scoring abstracts presented in 3 minute 'flash talks'

12:00

INDUSTRY SYMPOSIUM - Thermo Fisher Scientific

Ilaria Alborelli University Hospital Basel, Switzerland

“Plasma-based next-generation sequencing analysis of cancer-hotspot genomic alterations in non-small cell lung cancer”

12:30

LUNCH & TRADE EXHIBITION

13:00

POSTER DISCUSSION SESSION 2

Posters 54-106 will be presented

14:30

SESSION 3: Circulating Tumour Cells

Chair: Carlos Caldas

14:30

Caroline Dive CRUK Manchester Institute, UK

"Circulating Tumour Cells in lung cancer - lethal subclones and therapy testing 'avatars'"

15:00

Nicola Aceto University of Basel, Switzerland

"Features and vulnerabilities of circulating tumour cell clusters"

15:30

Carolina Reduzzi Istituto Nazionale Tumori, Italy

Proffered Paper 5: "Dual-positive cells circulating in the blood of cancer patients: tumor origin and clinical potential"

15:45

Evi Lianidou University of Athens, Greece

"Epigenetic alterations in CTCs and corresponding ctDNA"

16:15

COFFEE BREAK & TRADE EXHIBITION

16:45

Rui Neves UniKlinik Dusseldorf, Germany

Proffered Paper 6: "The molecular evolution of systemic metastatic castration resistant prostate cancer during therapy monitored by analysis of individual circulating tumour cells"

17:00

Klaus Pantel University Medical Centre Hamburg-Eppendorf, Germany

"Circulating Tumor Cells: biology and clinical applications as liquid biopsy"

17:30

PANEL DISCUSSION

Chaired by Sarah-Jane Dawson, the panel of invited speakers will tackle this important question.

"How do we move liquid biopsies from a research tool to part of routine decision making?"

19:00

Conference Dinner

Taverna Valtellinese

Optional ticketed dinner

Friday 17th May 2019

08:30

POSTER VIEWING & TRADE EXHIBITION

Coffee / tea available

08:40

INDUSTRY SPOTLIGHT - VyCAP

until 08:55

Arjan Tibbe VyCAP, Netherlands

"Solution for single cell analysis, identification and isolation"

09:00

SESSION 4: Novel Cancer Biomarkers in Blood

Chair: Alberto Bardelli

09:00

Federica Di Nicolantonio Candiolo Cancer Institute, Italy

"Cancer epigenetic alterations in cell free DNA"

09:30

Gabriella Sozzi Istituto Nazionale Tumori, Italy

"Circulating miRNAs as biomarkers for early detection and therapeutics of lung cancer"

10:00

Ruben Van Paemel Ghent University, Belgium

Proffered Paper 7: "Non-invasive classification of pediatric tumor types using reduced representation bisulfite sequencing of cell-free DNA: a proof-of-principle study"

10:15

Michael Speicher Medical University of Graz, Austria

"Epigenetic traces in plasma DNA"

10:45

COFFEE BREAK & TRADE EXHIBITION

11:15

Naveen Ramesh MD Anderson Cancer Center, USA

Proffered Paper 8: "Delineating Clonal Evolution During Therapeutic Resistance in Prostate Cancer by Whole Genome Plasma Sequencing"

11:30

Sarah-Jane Dawson Peter McCallum Cancer Centre, Australia

"Translational and clinical applications of ctDNA in solid and haematological malignancies"

12:00

Johann de Bono The Institute of Cancer Research, UK

"Improving drug development with liquid biomarkers"

12:30

SUMMARY & AWARDS

12:45

LUNCH & DEPART

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