Welcome to the European Association for Cancer Research
Connecting cancer researchers together
A Matter of Life or Death: From Basic Cell Death Mechanisms to Novel Cancer Treatments
Amsterdam, Netherlands : 1 - 3 February 2018
Scientific Programme
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FULL PROGRAMME AND SPEAKER ABSTRACTS
Click here to download the Full Programme and Abstract Book for the course.
Registration
Rode Hoed foyer
until 13:00
Welcome Lunch & Opening of the Trade Exhibition
Including tea/coffee
Conference Welcome
Oosterhuiszaal
Scientific Programme Committee
Session 1: MECHANISTIC INSIGHT IN the regulation of AUTOPHAGY AND the role of SENESCENCE as tumour suppressor
Chairs: Simone Fulda & Guillermo Velasco
Opening Keynote Lecture
Kevin Ryan Beatson Institute, UK
"Autophagy and cancer: issues we need to digest"
Tor Erik Rusten Oslo University Hospital, Norway
"Non-autonomous tumor growth support by autophagy"
Oriol de Barrios IDIBAPS, Spain
Proffered Paper 1: "The EMT-factor ZEB1 promotes tumor progression through inhibition of cell senescence"
EXHIBITOR INTRODUCTIONS
COFFEE BREAK & TRADE EXHIBITION
Oosterhuiszaal & Foyer
Session 2: REGULATION OF CLASSICAL AND NON-CLASSICAL MODES OF APOPTOSIS
Chairs: Eugenia Piddini & Kevin Ryan
EMBO Young Investigator Lecture
Ana J. García-Sáez Universität Tübingen, Germany
"Bax and Bak at the single molecule level: telling the twins apart"
Jan Paul Medema AMC, Netherlands
"Colorectal cancer, four subtypes with distinct biology"
POSTER DEFENCE SESSION 1
Lower Balcony
NETWORKING RECEPTION & TRADE EXHIBITION
Oosterhuiszaal & Foyer
With drinks & hot buffet dinner
Evening Keynote Lecture
Scott Dixon Stanford University, USA
"The regulation of ferroptosis in cancer cells"
POSTER VIEWING & TRADE EXHIBITION
Oosterhuiszaal & Lower Balcony
Coffee available to purchase
Session 3: Role of cell survival and death signaling in cancer susceptibility, tumour growth and therapy response
Chairs: Jan Paul Medema & John Silke
Eugenia Piddini University of Bristol, UK
"The role of cell competition in tumour promotion"
Peter de Keizer UMC Utrecht, Netherlands
"Targeted apoptosis of senescent cells against aging and cancer"
Yaron Fuchs Technion, Israel
Proffered Paper 2: "Caspase-3 Regulates YAP-dependent Cell Proliferation and Organ Size"
Michael Hahne CNRS / IGMM, France
Proffered Paper 3: "Primary cilia modulate susceptibility to colon carcinogenesis"
COFFEE BREAK & TRADE EXHIBITION
Oosterhuiszaal & Foyer
Stephen Tait Beatson Institute, UK
"Mitochondrial apoptosis and cancer: from phantom menace to a force awakens"
Giorgio Stassi Palermo University, Italy
"MAPK, PI3K and HER2 inhibition induces synthetic lethality in colorectal cancer stem cells regardless their mutational status"
BUFFET LUNCH & TRADE EXHIBITION
Oosterhuiszaal & Foyer
Session 4: Impact of cell death on immune responses to cancer and cancer therapies
Chairs: Ana J. García-Sáez & Manolis Pasparakis
Verena Jendrossek Universität Duisburg-Essen, Germany
"Normal tissue response to ionizing radiation and therapeutic targeting"
Sandra Demaria Weill Cornell Medical College, USA
"Mechanisms regulating the immunogenicity of radiation-induced cancer cell death"
Inge Verbrugge NKI, Netherlands
Proffered Paper 4: "Chemo-Radio-Immunotherapy: Cisplatin improves abscopal effects following radiotherapy and a-CD137/a-PD1 mAbs"
Jolien Bridelance VIB-UGent, Belgium
Proffered Paper 5: "Identification of molecular mechanisms essential for necroptosis execution by using a genome-wide CRISPR-Cas knockout screening"
Karin de Visser NKI, Netherlands
"The immune system: a double-edged sword in metastatic breast cancer"
POSTER DEFENCE SESSION 2
Lower Balcony
Coffee served
Round Table Discussions
Oosterhuiszaal
until 17.30
This session enables participants and speakers to converse informally in smaller groups. Participants are free to ask any questions they like and to move freely between the groups of different speakers.
CONFERENCE DINNER
Restaurant-Café In De Waag
Pre-booked optional extra
POSTER VIEWING & TRADE EXHIBITION
Oosterhuiszaal & Lower Balcony
Coffee available to purchase
Session 5: Cell death regulation in cancer and therapeutic targeting
Chairs: Verena Jendrossek & Stephen Tait
Andreas Villunger Medical University of Innsbruck, Austria
"The PIDDosome – a signalling platform controlling p53 activation"
Simone Fulda UCT Frankfurt, Germany
"Novel opportunities to target cell death pathways for cancer therapy"
Prashanthi Ramesh AMC, Netherlands
Proffered Paper 6: "BCL-xL specific stem cell resistance is maintained through colon cancer transformation and allows identification of optimal combination strategies"
Silvia Vega-Rubin-de-Celis DKFZ, Germany
Proffered Paper 7: "Inhibition of HER2 tumorigenesis by Beclin 1 and an autophagy-inducing peptide"
COFFEE BREAK & TRADE EXHIBITION
Oosterhuiszaal & Foyer
John Silke Walter and Eliza Hall Institute, Australia
"Pump it Up - Will Smac-mimetics make it into the clinic? If so how and when?"
Guillermo Velasco Complutense University, Spain
"Molecular mechanisms involved in the stimulation of autophagy-mediated cancer cell death"
Evangelos Kondylis University of Cologne, Germany
"IKK/NF-kB and RIPK1 signalling in cell death and inflammation"
Closing summary
Scientific Programme Committee
Poster Prizes and Meeting Bursaries will be presented by Verena Jendrossek
LUNCH AND DEPART
Rode Hoed foyer
Key dates
Travel Grant application deadline:
10 November 2017
Abstract submission deadline:
20 November 2017
Registration deadline:
05 January 2018
“Excellent meeting for researchers interested in tumour cell-related cell death mechanisms. Very efficient way to become up-to-date. Very good interaction, networking and communication among the participants.”
“Convincing overall conference package: good speakers/talks, very well structured program and good interaction with other participants possible due to small but "relevant" audience. And then... Amsterdam and the conference venue!”
“Well organized, renowned international speakers, fruitful discussions and great atmosphere.”
Feedback from participants in the 2016 edition
