POSTER VIEWING & TRADE EXHIBITION

Oosterhuiszaal & Lower Balcony

Coffee available to purchase

Session 3: Role of cell survival and death signaling in cancer susceptibility, tumour growth and therapy response

Chairs: Jan Paul Medema & John Silke

Eugenia Piddini University of Bristol, UK

"The role of cell competition in tumour promotion"

Peter de Keizer UMC Utrecht, Netherlands

"Targeted apoptosis of senescent cells against aging and cancer"

Yaron Fuchs Technion, Israel

Proffered Paper 2: "Caspase-3 Regulates YAP-dependent Cell Proliferation and Organ Size"

Michael Hahne CNRS / IGMM, France

Proffered Paper 3: "Primary cilia modulate susceptibility to colon carcinogenesis"

COFFEE BREAK & TRADE EXHIBITION

Oosterhuiszaal & Foyer

Stephen Tait Beatson Institute, UK

"Mitochondrial apoptosis and cancer: from phantom menace to a force awakens"

Giorgio Stassi Palermo University, Italy

"MAPK, PI3K and HER2 inhibition induces synthetic lethality in colorectal cancer stem cells regardless their mutational status"

BUFFET LUNCH & TRADE EXHIBITION

Oosterhuiszaal & Foyer

Session 4: Impact of cell death on immune responses to cancer and cancer therapies

Chairs: Ana J. García-Sáez & Manolis Pasparakis

Verena Jendrossek Universität Duisburg-Essen, Germany

"Normal tissue response to ionizing radiation and therapeutic targeting"

Sandra Demaria Weill Cornell Medical College, USA

"Mechanisms regulating the immunogenicity of radiation-induced cancer cell death"

Inge Verbrugge NKI, Netherlands

Proffered Paper 4: "Chemo-Radio-Immunotherapy: Cisplatin improves abscopal effects following radiotherapy and a-CD137/a-PD1 mAbs"

Jolien Bridelance VIB-UGent, Belgium

Proffered Paper 5: "Identification of molecular mechanisms essential for necroptosis execution by using a genome-wide CRISPR-Cas knockout screening"

Karin de Visser NKI, Netherlands

"The immune system: a double-edged sword in metastatic breast cancer"

POSTER DEFENCE SESSION 2

Lower Balcony

Coffee served

Round Table Discussions

Oosterhuiszaal

until 17.30

This session enables participants and speakers to converse informally in smaller groups. Participants are free to ask any questions they like and to move freely between the groups of different speakers.

CONFERENCE DINNER

Restaurant-Café In De Waag

Pre-booked optional extra

POSTER VIEWING & TRADE EXHIBITION

Oosterhuiszaal & Lower Balcony

Coffee available to purchase

Session 5: Cell death regulation in cancer and therapeutic targeting

Chairs: Verena Jendrossek & Stephen Tait

Andreas Villunger Medical University of Innsbruck, Austria

"The PIDDosome – a signalling platform controlling p53 activation"

Simone Fulda UCT Frankfurt, Germany

"Novel opportunities to target cell death pathways for cancer therapy"

Prashanthi Ramesh AMC, Netherlands

Proffered Paper 6: "BCL-xL specific stem cell resistance is maintained through colon cancer transformation and allows identification of optimal combination strategies"

Silvia Vega-Rubin-de-Celis DKFZ, Germany

Proffered Paper 7: "Inhibition of HER2 tumorigenesis by Beclin 1 and an autophagy-inducing peptide"

COFFEE BREAK & TRADE EXHIBITION

Oosterhuiszaal & Foyer

John Silke Walter and Eliza Hall Institute, Australia

"Pump it Up - Will Smac-mimetics make it into the clinic? If so how and when?"

Guillermo Velasco Complutense University, Spain

"Molecular mechanisms involved in the stimulation of autophagy-mediated cancer cell death"

Evangelos Kondylis University of Cologne, Germany

"IKK/NF-kB and RIPK1 signalling in cell death and inflammation"

Closing summary

Scientific Programme Committee

Poster Prizes and Meeting Bursaries will be presented by Verena Jendrossek

LUNCH AND DEPART

Rode Hoed foyer