Defence is the Best Attack: Immuno-Oncology Breakthroughs

Barcelona, Spain : 11 - 13 March 2019

Scientific Programme

Monday 11th March 2019

12:00

Registration

Posters may be put up from 12:00

13:00

WELCOME LUNCH & TRADE EXHIBITION

14:00

Conference welcome

Scientific Programme Committee

14:15

Session 1

Chair: Joan Seoane

14:15

Pablo Umaña Roche Innovation Center Zurich, Switzerland

"Redirecting T-cells for Cancer Immunotherapy using Next Generation Bispecific Antibodies and Fusion Proteins"

14:45

Karin de Visser NKI, Netherlands

"Dissecting cancer cell-intrinsic mechanisms dictating the immune landscape of breast cancer"

15:15

Yotam Bar-Ephraim Hubrecht Institute, Netherlands

Proffered Paper 1: "Raising T cells against tumour-derived neo-antigens using epithelial organoid cultures"

15:30

Elena Garralda VHIO, Spain

"Challenges in early drug development of IO agents"

16:00

EXHIBITOR INTRODUCTIONS

Hear about the equipment and services offered by the companies in the trade exhibition.

16:10

COFFEE BREAK

16:40

Session 2

Chair: Johanna Joyce

16:40

POSTER SPOTLIGHTS

3 top-scoring abstracts will be presented in short 'flash talks' of 3 minutes each.

16:50

Neta Erez Tel Aviv University, Israel

Proffered Paper 2: "Shaping the immune landscape: Cancer-Associated Fibroblasts drive Th2 immunity in breast cancer progression and metastasis"

17:05

Luca Gattinoni National Cancer Institute, USA

"Harnessing T memory stem cells for adoptive cell transfer therapy of cancer"

17:35

Andrea Schietinger MSKCC, USA

"Molecular mechanisms defining tumor-specific T cell dysfunction and therapeutic reprogrammability"

18:05

EMBO Keynote Lecture

Richard Flavell Yale University School of Medicine, USA

"Study of the interface between human cancers and the human immune system in novel humanized mice"

18:50

NETWORKING RECEPTION

with drinks and a hot buffet dinner

19:30

POSTER DISCUSSION SESSION 1

Odd numbered posters will be presented

Tuesday 12th March 2019

09:00

POSTER VIEWING

tea/coffee available

09:30

Industry SPOTLIGHT 1 - Nexcelom Bioscience

Sun Yung

“Novel plate-based detection method for T cell activation/proliferation, migration and cytotoxicity assay using image cytometry.”

09:45

Session 3

Chair: Andrea Schietinger

09:45

Alena Gros VHIO, Spain

"Harnessing the personalized antitumor T-cell response to treat cancer"

10:15

Johanna Joyce University of Lausanne, Switzerland

"Exploring and Therapeutically Exploiting the Tumour Microenvironment"

10:45

Keynote Lecture

George Coukos University of Lausanne, Switzerland

"Orchestration of antitumor immune response. Lesson for immunotherapy from the tumor microenvironment"

11:30

COFFEE BREAK

12:05

Session 4

Chair: Karin de Visser

12:05

POSTER SPOTLIGHTS

3 top-scoring abstracts will be presented in short 'flash talks' of 3 minutes each.

12:15

Joan Seoane VHIO, Spain

"Embryology meets Oncology. The role of LIF in cancer"

12:45

Marit Melssen University of Virginia, USA

Proffered Paper 3: "Formation and function of CD49a+ and CD49b+ CD8 T cells in a murine breast cancer model"

13:00

Sergio Quezada UCL Cancer Institute, UK

“T cell evolution in non-small cell lung cancer”

13:30

Industry SYMPOSIUM - Thermo Fisher Scientific

Tim Looney

"Predicting immunotherapy response and adverse events through next generation sequencing of peripheral blood T cell repertoires"

14:00

LUNCH

15:00

POSTER DISCUSSION SESSION 2

Even numbered posters will be presented. Tea & coffee will be available.

16:30

Session 5

Chair: Sergio Quezada

16:30

Graham Pawelec University of Tübingen, Germany

"Immunotherapy of Cancer: Triumphs and Challenges and the Impact of Immunosenescence"

17:00

Danique Duits NKI, Netherlands

Proffered Paper 4: "Systemic expansion of pro-metastatic neutrophils is enhanced by MET amplification in breast cancer"

17:15

Kris Thielemans VUB, Belgium

"mRNA therapeutics: ex-vivo and in-vivo modification of antigen presenting cells"

17:45

DISCUSSION FORUM

until 18:45

The discussion will be led by Joan Seoane, Zlatko Trajanosky and George Coukos, and participants are invited to contribute to the conversation.

"How to introduce precision medicine principles to immuno-oncology"

19:30

Conference Dinner

El Principal del Eixample

Ticketed optional extra

Wednesday 13th March 2019

09:00

POSTER VIEWING

tea/coffee available

09:30

Industry SPOTLIGHT 2 - 10x Genomics

Hannes Arnold

"Single Cell and Spatial Gene Expression Analysis of the Tumor Microenvironment"

09:45

Session 6

Chair: Alena Gros

09:45

Núria Lopez-Bigas ICREA & IRB Barcelona, Spain

"Biological and clinical relevance of tumor mutations"

10:15

Zlatko Trajanosky Innsbruck Medical University, Austria

"Computing and probing immunity in colorectal cancer"

10:45

Jitske van den Bulk LUMC, Netherlands

Proffered Paper 5: "Detection of neo-antigen-specific T cell responses in low mutation burden colorectal cancers for personalized therapies"

11:00

COFFEE BREAK

11:30

Miguel Sanmamed University of Navarra, Spain

"Novel patient-derived tumor models for immunotherapy development”

12:00

Closing Keynote

Laurence Zitvogel Gustave Roussy, France

"The unsuspected role of gut microbiota in cancer therapies"

12:45

Summary & Awards

Scientific Programme Committee

13:00

LUNCH & DEPART

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