Registration

Planck Lobby

Including tea/coffee

Conference Welcome

Andrew Ewald - Conference Chair

Opening Keynote Lecture

Chair: Emmy Verschuren

Hans Clevers Hubrecht Institute, Netherlands

"Lgr5 stem cell-based organoids in human cancer research"

Icebreaker Introductions

Planck Lobby

An opportunity to make some new connections and meet those with similar research interests.

WELCOME BUFFET & TRADE EXHIBITION

Meitner Hall & Goethe Hall

Drinks & hot buffet

POSTER VIEWING & TRADE EXHIBITION

Meitner Hall & Goethe Hall

Including tea/coffee

Session 1: Molecular and cellular regulation of metastasis

Chair: Ellen Van Obberghen-Schilling

Andrew Ewald Johns Hopkins, USA

"Regulation of metastasis by intercellular interactions"

Margaret Frame IGMM Edinburgh, UK

"Targeting the multitasking adhesion kinases as combination therapies"

Elizabeth Pavez Loriè Leibniz Institute of Environmental Medicine, Germany

Proffered Paper 1: "Cyclosporin A is promoting tumor like invasion in a long-term human skin equivalent"

EXHIBITOR INTRODUCTIONS

Hear about the equipment and services offered by the companies in the trade exhibition.

COFFEE BREAK & TRADE EXHIBITION

Meitner Hall & Goethe Hall

Julie Pannequin IGF Montpellier, France

Proffered Paper 2: "Circulating tumor cells from patients with colorectal cancer display cancer stem cell hallmarks in ex-vivo culture"

Matthias Lütolf EPFL, Switzerland

"Engineering organoid development"

Poster Spotlights

Four top-scoring abstracts will be presented in short 'flash talks' of 2 minutes each.

INDUSTRY SYMPOSIUM - Lonza

Jenny Schroeder Lonza, Germany

“Advanced Cell Culture Solutions for Primary Human Cells”

BUFFET LUNCH & TRADE EXHIBITION

Meitner Hall & Goethe Hall

POSTER DISCUSSION SESSION 1

Including tea/coffee

Session 2: The immune microenvironment and immunotherapy in cancer

Chair: Peter Friedl

Immuno Keynote Lecture

Ron Germain National Institutes of Health, USA

"Imaging immunity in many colors and dimensions: developing a detailed spatiotemporal understanding of host defense"

Bettina Weigelin RIMLS / MD Anderson, Netherlands/USA

"Cytotoxic T cell function in solid tumors and bone metastasis: implications for immunotherapy"

Sofia Rebelo iBet, Portugal

Proffered Paper 3: "3D-3-culture: unveiling macrophage plasticity in the tumor microenvironment"

Reinhold Förster Institute for Immunology, Hannover, Germany

"Lymph node homing of lymph-derived immune cells"

Career Forum

Liebig Vault

Spaces are limited, and sign up will open after the registration deadline. The session will finish at 17:30.

POSTER VIEWING & TRADE EXHIBITION

Meitner Hall & Goethe Hall

Including tea/coffee

Meet the Expert

Margaret Frame IGMM Edinburgh, UK

Prof. Frame will share from her personal perspective and experiences. There will be a chance to ask questions.

Session 3: Microenvironmental and metabolic regulation of cancer invasion

Chair: Maria Vinci

Peter Friedl Radboud UMC / MD Anderson CC, Netherlands/USA

"Collective cancer cell invasion: plasticity and interconversions"

Danijela Vignjevic Institut Curie, France

"Fibroblasts role in gut homeostasis and cancer invasion"

COFFEE BREAK & TRADE EXHIBITION

Christopher Hanley University Of Southampton, UK

Proffered Paper 4: "3D co-culture of tumor organoids with autologous stromal cells induces keratin-14 expression and invasion in multiple models of ductal breast cancer"

Aneta Gandalovičová Charles University, Czech Republic

Proffered Paper 5: "Inflammation-associated signaling is associated with the amoeboid invasion mode in cancer cells"

Ellen Van Obberghen-Schilling Institute of Biology Valrose, France

"ECM landscape and tumor progression"

Poster Spotlights

Four top-scoring abstracts will be presented in short 'flash talks' of 2 minutes each.

INDUSTRY SYMPOSIUM - Nexcelom Bioscience

Somaieh Hedayat The Institute of Cancer Research, UK

"Patients derived organoids (PDOs) to model therapy response ex vivo"

Muge Sarper The Institute of Cancer Research, UK

"Large scale phenotypic drug screen on biomimetic 3D models"

BUFFET LUNCH & TRADE EXHIBITION

Meitner Hall & Goethe Hall

POSTER DISCUSSION SESSION 2

Including tea/coffee

Session 4: Smart microenvironments I

Chair: Emmy Verschuren

Fanny Jaulin Gustave Roussy, France

"Apico-basolateral polarity in colorectal carcinomas dissemination"

Claudia Fischbach-Teschl Cornell University, USA

"Biomaterials approaches to analyze ECM dynamics in obesity-associated breast cancer"

Nicola Valeri The Institute of Cancer Research, UK

Proffered Paper 6: "Patient-derived organoids model treatment response of metastatic gastrointestinal cancers"

Maria Carla Parrini Institut Curie, France

Proffered Paper 7: "Tumor-on-chip platforms for ex vivo characterization of tumor microenvironments and of their responses to anti-cancer drugs"

Janine Erler BRIC, Denmark

"Modelling metastasis using native ECM"

Conference Debate

Speakers will present opposing sides of the argument and there will be a chance to ask questions. A vote will be taken before and after.

Chair: Emmy Verschuren | Defending: Don Ingber | Opposing: Peter Friedl

"Smart 3D culture will replace animal experiments"

Drinks Reception & Conference Dinner

Restaurant Harnack Haus

Ticketed optional extra.

POSTER VIEWING & TRADE EXHIBITION

Meitner Hall & Goethe Hall

Including tea/coffee

Session 5: Smart microenvironments II

Chair: Andrew Ewald

Anne Rios Princess Maxima Center, Netherlands

"Investigating the cellular dynamics of organ development and cancer using 3D imaging"

Maria Vinci Bambino Gesu' Children's Hospital, Italy

"Interclonal and heterocellular interactions in paediatric High Grade Glioma"

INDUSTRY SYMPOSIUM - JSR Life Sciences

Henry Li Crown Bioscience, USA

“Creating patient derived experimental platform for in vitro screening by using the largest annotated PDX library”

COFFEE BREAK & TRADE EXHIBITION

Dik van Gent Erasmus MC, Netherlands

Proffered Paper 8: "The RECAP test: measuring Homologous recombination deficiency in living tumor tissue"

Emmy Verschuren FIMM, Finland

"Histopathology-specific lung cancer phenotypes as disease vulnerabilities"

Closing Keynote

Chair: Maria Vinci

Don Ingber Wyss Institute, USA

"From Organs-on-Chips to a Human Body-on-Chips"

Summary & Awards

Ellen Van Obberghen-Schilling - incoming Conference Chair

LUNCH, TRADE EXHIBITION CLOSES, DEPART

until 13:30