Mechanisms to Therapies: Innovations in Cancer Metabolism

Bilbao, Spain : 9 - 11 October 2018

Scientific Programme

Tuesday 9th October 2018

10:30

Registration

Until 11:30

Coffee available

11:30

Conference Welcome

Scientific Programme Committee

11:45

ASEICA Keynote Lecture

William Kaelin, Jr. Howard Hughes Medical Institute and Dana Farber Cancer Institute, USA

"The VHL Tumor Suppressor Protein:  Insights into Oxygen Sensing, Cancer Metabolism and Drugging the Undruggable"

Session 1 - Oncogenic metabolic signalling

12:30

Brendan Manning HSPH, USA

"The PI3K-mTOR Signaling Network and the Control of Anabolic Cell Growth"

13:00

LUNCH & MEET THE EXPERT

14:30

Alejo Efeyan CNIO, Spain

"Oncogenic Nutrient Signaling in B cell Lymphoma"

15:00

Reuben Shaw The Salk Institute, USA

“The AMPK pathway: good signals for bad times”

15:30

Heather Christofk UCLA Jonsson Comprehensive Cancer Center, USA

"Metabolic Regulation of Cell State"

16:00

Author to be selected

Proffered Paper 1

16:15

COFFEE BREAK

Session 2 - Metabolic wiring in cancer

16:45

Sarah-Maria Fendt VIB-KU Leuven Center for Cancer Biology, Belgium

"Cancer metabolism during metastasis formation"

17:15

Ayelet Erez Weizmann Institute of Science, Israel

"The role of amino-acid metabolism in carcinogenesis"

17:45

Matt Vander Heiden Massachusetts Institute of Technology, USA

"How metabolisum supports tumour progression"

18:15

Author to be selected

Proffered Paper 2

18:30

Free evening to enjoy Bilbao!

Wednesday 10th October 2018

Session 3 - Metabolic control of the epigenome

10:00

Raul Mostoslavsky MGH Cancer Center, Harvard Medical School, USA

"Linking epigenetics, metabolism and cancer: SIRT6 provides new clues"

10:30

Lydia Finley Memorial Sloan Kettering Cancer Center, USA

"Metabolic coordination of p53-dependent tumor suppression"

11:00

Author to be selected

Proffered Paper 3

11:15

EXHIBITOR INTRODUCTIONS

A fun session to introduce the companies who are exhibiting at the conference

11:20

COFFEE BREAK

Trade exhibition opens

11:50

Christian Frezza University of Cambridge, UK

"Fumarate hydratase and renal cancer: oncemetabolites and beyond"

12:20

Navdeep Chandel Northwestern University, USA

"Mitochondria and Cancer"

12:50

LUNCH & POSTER DEFENCE SESSION 1

Session 4 -Metabolic heterogeneity & tumour progression

14:50

Salvador Aznar-Benitah ICREA, IRB Barcelona, Spain

"Metastasis-initiating cells: an epigenetic link between between metastasis and what we eat"

15:20

Arkaitz Carracedo CIC bioGUNE, Spain

"Metabolic plasticity in the ever-changing tumor environment"

15:50

Author to be selected

Proffered Paper 4

16:05

COFFEE BREAK

16:35

Carla Martins University of Cambridge, UK

"Exploiting the metabolic heterogeneity of mutant Kras lung tumors to improve targeting"

17:05

Celeste Simon University of Pennsylvania, USA

"Metabolism, Inflammation, and Tumor Progression"

17:35

PANEL DISCUSSION

Until 18:35

20:30

Optional Conference Dinner

Kafe Antzokia

Thursday 11th October 2018

Session 5 - Targeting stroma metabolism

09:00

Peter Carmeliet VIB-KU Leuven Center for Cancer Biology, Belgium

"Angiogenesis revisited: Role and (therapeutic) implication of endothelial metabolism"

09:30

Susan Kaech The Salk Institute, USA

"Anti-tumor T cells- you are what you eat"

10:00

Marina Kreutz University Hospital Regensburg, Germany

"Warburg meets immunology: Immunomodulation by lactic acid"

10:30

Author to be selected

Proffered Paper 5

10:45

COFFEE BREAK

Session 6 - Bench to bedside/ Targeting metabolic liabilities

11:15

Ralph Deberardinis Children’s Medical Center Research Institute, USA

"Understanding metabolic heterogeneity in human cancer"

11:45

Alec Kimmelman Perlmutter Cancer Center, USA

"Identifying Metabolic Dependencies in Pancreatic Cancer"

12:15

Author to be selected

Proffered Paper 6

12:30

LUNCH & POSTER DEFENCE SESSION 2

14:30

Scott Biller Agios, USA

"Cancer Metabolism from Bench to the Clinic"

15:00

EMBO Keynote Lecture

Karen Vousden The Francis Crick Institute, UK

"p53 and metabolism: cancer and beyond"

15:45

CLOSING CEREMONY & PRESENTATION OF AWARD CERTIFICATES

Until 16:00

Scientific Programme Committee

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