The European Association for Cancer Research
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University of Duisburg-Essen, Germany
1 Post Doc and 3 PhD-positions (temporary) in Experimental Oncology
Institute for Cell Biology (Tumour Research), Department of Molecular Cell
Biology
available in following projects
- Role of the microenvironment for growth and therapy resistance of prostate cancer
- Molecular basis of radiation-induced pneumopathy
“Role of the microenvironment for growth and
therapy resistance of prostate cancer”
Malignant cells of patients suffering from solid tumour, e.g. prostate
cancer are often characterised by deregulated activity of the phosphatidylinositol-3-kinase
(PI3K) signalling pathway with up-regulated activity of the survival kinase
protein kinase B (PKB/Akt). Apart from genetic alterations within the tumor
cells such as loss or inactivation of PTEN, environmental factors (inflammation,
growth factors, tumour- stroma interactions) are suggested to contribute
to upregulated activity of this survival kinase and may therefore contribute
to tumorigenesis and therapy resistance.
Aim of the proposed project is to analyse the impact of the microenvironment
on growth, survival signaling and therapy response of human solid tumor
cells in vitro with a focus on inflammation- and adhesion-related events
as well as tumour-stroma interactions.
“Molecular basis of radiation-induced pneumopathy”
Radiation-induced pneumonitis and fibrosis constitute dose-limiting side
effects of total body irradiation and of radiotherapy for thorax associated
neoplasms. However, the network of pathophysiologic events is not completely
understood. In particular, the molecular mechanisms linking acute tissue
damage to chronic inflammation and sustained repair processes remain
to be defined. Moreover, it is still controversial whether the inflammatory
reaction is a prerequisite for progression to lung fibrosis. Aim of the
proposed project is to study the putative connection between radiation-induced
tissue damage, inflammation and the development of lung fibrosis in vitro
and in a mouse model. The role of specified signaling molecules suggested
to be involved in the pathophysiology of this process shall be studied
by using genetically defined mouse strains. The detailed knowledge of
the underlying mechanisms is a prerequisite for the design of radioprotective
treatment approaches.
ÞApplication:
We search for highly motivated young researchers with an excellent scientific
record and a strong interest in interdisciplinary projects. A backgound
in molecular biology, immunology and/or animal experiments is favorable.
Please send your application including CV, academic record, tow potential
referees and an indication of the preferred field of research to:
Prof. Dr. rer. nat. V. Jendrossek
Institute of Cell Biology
Department of Molecular Cell Biology
University of Duisburg-Essen
Virchowstrasse 173
45122 Essen
Phone: +49-201-7233380
Fax: +49-0201-7235904
E-mail applications should be sent to verena.jendrossek@uni-duisburg-essen.de
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Jobs and Study Opportunities
PhD students and Postdoc scientists to study autophagy in cancer, Università “A. Avogadro”, Novara, Italy
Enthusiastic and highly motivated PhD students (3 positions) and postdoctoral scientists (3 positions) are sought to work on the role of autophagy in cancer progression and chemoresistance at the Department of Medical Sciences, University Amedeo Avogadro in Novara, Italy.
Grant Application Announcement
World Cancer Research Fund (WCRF) International is now inviting applications for grants worldwide to fund research into the effects of food, nutrition and physical activity on cancer. WCRF International may also co-fund breast cancer project grants with Breast Cancer Campaign.
Postdoctoral positions to work on SUMO and Ubiquitin
MRC funded 4 year posts (X2)
SCILLS funded 4 year posts (X2)
BBSRC funded 2.5 year post
Informatics Data Manager 4 year post
Enthusiastic and highly motivated postdoctoral scientists are sought to work on the role of ubiquitin and SUMO in pathways contributing to disease in humans. The successful applicants will join a team of researchers tackling these problems in the laboratory of Ron Hay. This is a well resourced laboratory in the College of Life Sciences which has excellent facilities for high-resolution mass spectrometry, X-ray Crystallography, light and electron microscopy, flow cytometry and whole genome siRNA screening.
Positions at the Cancer Epigenetics and Biology Program (PEBC), Barcelona
1 Junior Group Leader (Includes funding for reagents and personnel)
1 Research Associate
3 Postdoctoral Researchers
3 PhD Students
3 Technicians (Including a confocal specialist)
1 Scientific Management Officer
The Catalan Institute of Oncology (Institut Català d'Oncologia, ICO) is a nonprofitable public company, created in March 1995 and member of the Servei Català de la Salut (Catalan Health Service). The Institute is a centre of integral oncology assistance, which, according to international tendency, integrates in only one organization all the elements and the efforts to fight effectively and efficiently against cancer.
University of Nice, CNRS, Inserm
Five Group Leaders
CANCER RESEARCH CENTER
The Inserm Federative Institute (IFR50, www.ifr50.fr/) and the CNRS Research Institute of Developmental Biology & Cancer (UMR6543, www.unice.fr/isdbc/), both affiliated to the University of Nice are preparing the emergence of a Cancer Research Center regrouping world class research teams in the field of Cancer Biology/Stem Cells and in close cooperation with the University Hospital and Cancer Center Antoine Lacassagne of Nice.
Postdoc for epigenetic analyses in breast carcinogenesis, Heidelberg University & DKFZ
Division of Toxicology and Cancer Risk Factors. The project will involve the establishment of high throughput methods to quantify methylation levels of DNA using MassARRAY technology. In addition, molecular-biological techniques will be used for the functional analysis of identified genes.
University of Duisburg-Essen, Germany
1 Post Doc and 3 PhD-positions in Experimental Oncology
Institute for Cell Biology (Tumour Research), Department of Molecular Cell
Biology
Postdoctoral position available
The package includes a competitive salary 36.000 euros/year, managerial and scientific training and a number of benefits.
IFOM-IEO Campus, Milan, Italy
For further information >Post-Doctoral Position, The Immunotherapy & Gene Therapy Unit
The Immunotherapy & Gene Therapy Unit seeks a candidate with experience in immunology to study regulatory T cells expansion, conversion and inactivation in tumor bearers using a variety of mixed bone marrow chimeras as well as gene shut down in bone marrow donors.