Seed and Soil: In Vivo Models of Metastasis

Berlin, Germany : 27 - 29 November 2017

Scientific Programme

Monday 27th November 2017

14:00

Registration

Planck Lobby

until 15:30

15:00

Coffee available

Meitner Salle

15:30

Conference Welcome

Hahn Lecture Hall

Scientific Programme Committee

15:45

Opening Keynote Lecture

Robert Kerbel University of Toronto, Canada

"How The Organ Site of Metastases Can Impact Response to Antiangiogenic Drug Based Therapies"

16:45

CONFERENCE DEBATE

Defending: Hellmut Augustin || Opposing: Yibin Kang

“Our current animal models for studying metastasis produce experimental data that have little relevance for treating human disease”

17:45

EXHIBITOR INTRODUCTIONS

A fun session to introduce the companies who are exhibiting at the conference.

17:50

Welcome Reception

Planck Lobby

Trade exhibition opens

18:30

POSTER DEFENCE SESSION 1

until 20:00

Odd numbered posters (1,3,5 etc) will be presented in this session.

Tuesday 28th November 2017

08:00

POSTER PREVIEW

Meitner Salle

coffee available

Session 1: New models of metastasis

Chair: Janine Erler

09:00

Yibin Kang Princeton University, USA

"What can mouse mammary gland development tell us about breast cancer metastasis?"

09:30

Neta Erez Sackler School of Medicine, Israel

"Neuroinflammation and astrogliosis facilitate melanoma brain tropism and metastasis"

10:00

Alberto Hernández-Barranco CNIO, Spain

Proffered Paper 1: "Modulation of the pre-metastatic lymph node niche by melanoma cells through secreted exosomes"

10:15

Jonathan Sleeman University of Heidelberg, Germany

"A new role for VEGF-C in metastatic conditioning of the lung"

10:45

COFFEE BREAK

Meitner Salle

Session 2: Imaging metastasis

Chair: Neta Erez

11:15

Peter Friedl MD Anderson Cancer Center, USA

"Plasticity of cancer cell invasion and metastasis"

11:45

Chris Madsen Lund University, Sweden

"Imaging ECM remodelling during cancer progression and metastasis"

12:15

Adam Marcus Emory University, USA

Proffered Paper 2: "Using an image-guided genomics platform to probe the phenotypic heterogenetiy of collective cancer invasion"

12:30

Veronika te Boekhorst MD Anderson Cancer Center, USA

Proffered Paper 3: "Calpain-2 induced shutdown of β1 integrin function controls amoeboid reprogramming and dissemination under hypoxic challenge"

12:45

SATELLITE SYMPOSIUM - ELITE SPONSOR

Lecture Hall

13:15

LUNCH

Laue-Hall & Restaurant

14:15

POSTER DEFENCE SESSION 2

Meitner Salle

Even numbered posters (2,4,6 etc) will be presented in this session.

Session 3: Transgenic models of metastasis

Chair: Chris Madsen

15:45

Karin de Visser NKI, Netherlands

"Dissecting pro-metastatic cancer - immune interactions utilizing genetically engineered mouse models of metastatic breast cancer"

16:15

Hellmut Augustin German Cancer Research Center Heidelberg, Germany

"Novel preclinical models of primary tumor growth and metastasis"

16:45

Ophir Shani Sackler School of Medicine, Israel

Proffered Paper 4: "Dynamic co-evolution of lung fibroblasts in the metastatic microenvironment during breast cancer metastasis"

17:00

Irwin Gelman Roswell Park Cancer Institute, USA

Proffered Paper 5: "SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts"

17:15

ROUND TABLE DISCUSSIONS

Einstein Lounge

Until 18:30. Beverages may be purchased from the bar

This session enables participants and speakers to converse informally in smaller groups. Participants are free to ask any questions they like and to move freely between the tables of different speakers.

19:30

Drinks Reception & Conference Dinner

Join us for a drink in the Planck Lobby, followed by the Conference Dinner in Liebig Vault. This is an optional event with tickets limited to 110.

Wednesday 29th November 2017

08:00

POSTER PREVIEW

Meitner Salle

Coffee available

09:00

Meet the Expert

Professor Janine Terra Erler will share from her personal perspective and experiences

Session 4: Modelling metastasis

Chair: Jonathan Sleeman

09:30

Bin-Zhi Qian University of Edinburgh, UK

"Macrophage heterogeneity in breast cancer bone metastasis"

10:00

EMBO Keynote Lecture

Erik Sahai The Francis Crick Institute, UK

"Role of the microenvironment in cancer invasion and therapy response"

10:30

COFFEE BREAK

Meitner Salle

11:00

Rachel Eyre University of Manchester, UK

Proffered Paper 6: "Targeting IL-1β-Wnt signalling to prevent breast cancer colonisation in the bone microenvironment"

11:15

Ulrike Stein MDC, Germany

"Preclinical mouse models for exploring and exploiting novel cancer metastasis biomarkers"

11:45

Closing Keynote Lecture

Andreas Trumpp DKFZ, Germany

"Cellular and Molecular Deconvolution of Human Pancreatic and Breast Cancers"

12:30

Closing Summary

Scientific Programme Committee

Poster Prizes and Meeting Bursaries will be presented

12:45

LUNCH AND DEPART

Planck Lobby

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